Identity
HGNC
LOCATION
1q42.11
LOCUSID
ALIAS
CENP-30,Fbx28
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23219
MIM: 609100
HGNC: 29046
Ensembl: ENSG00000143756
Variants:
dbSNP: 23219
ClinVar: 23219
TCGA: ENSG00000143756
COSMIC: FBXO28
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000143756 | ENST00000366862 | Q9NVF7 |
| ENSG00000143756 | ENST00000366862 | A0A024R3Q6 |
| ENSG00000143756 | ENST00000424254 | Q9NVF7 |
| ENSG00000143756 | ENST00000523990 | B4E0H5 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38267923 | 2024 | FBXO28 promotes cell proliferation, migration and invasion via upregulation of the TGF-beta1/SMAD2/3 signaling pathway in ovarian cancer. | 1 |
| 38267923 | 2024 | FBXO28 promotes cell proliferation, migration and invasion via upregulation of the TGF-beta1/SMAD2/3 signaling pathway in ovarian cancer. | 1 |
| 37348029 | 2023 | FBXO28 promotes proliferation, invasion, and metastasis of pancreatic cancer cells through regulation of SMARCC2 ubiquitination. | 2 |
| 37596321 | 2023 | FBXO28 suppresses liver cancer invasion and metastasis by promoting PKA-dependent SNAI2 degradation. | 1 |
| 37348029 | 2023 | FBXO28 promotes proliferation, invasion, and metastasis of pancreatic cancer cells through regulation of SMARCC2 ubiquitination. | 2 |
| 37596321 | 2023 | FBXO28 suppresses liver cancer invasion and metastasis by promoting PKA-dependent SNAI2 degradation. | 1 |
| 33280099 | 2021 | FBXO28 causes developmental and epileptic encephalopathy with profound intellectual disability. | 6 |
| 33280099 | 2021 | FBXO28 causes developmental and epileptic encephalopathy with profound intellectual disability. | 6 |
| 31678254 | 2020 | SCF(FBXO28)-mediated self-ubiquitination of FBXO28 promotes its degradation. | 5 |
| 31678254 | 2020 | SCF(FBXO28)-mediated self-ubiquitination of FBXO28 promotes its degradation. | 5 |
| 29587369 | 2018 | An SCF(FBXO28) E3 Ligase Protects Pancreatic β-Cells from Apoptosis. | 4 |
| 30160831 | 2018 | A novel FBXO28 frameshift mutation in a child with developmental delay, dysmorphic features, and intractable epilepsy: A second gene that may contribute to the 1q41-q42 deletion phenotype. | 5 |
| 29587369 | 2018 | An SCF(FBXO28) E3 Ligase Protects Pancreatic β-Cells from Apoptosis. | 4 |
| 30160831 | 2018 | A novel FBXO28 frameshift mutation in a child with developmental delay, dysmorphic features, and intractable epilepsy: A second gene that may contribute to the 1q41-q42 deletion phenotype. | 5 |
| 28179588 | 2017 | TP53-based interaction analysis identifies cis-eQTL variants for TP53BP2, FBXO28, and FAM53A that associate with survival and treatment outcome in breast cancer. | 7 |
Citation
Dessen P
FBXO28 (F-box protein 28)
Atlas Genet Cytogenet Oncol Haematol. 2013-11-01
Online version: http://atlasgeneticsoncology.org/gene/53564/fbxo28-(f-box-protein-28)
