SOX21 (SRY-box transcription factor 21)

2013-11-01  

Identity

HGNC
LOCATION
13q32.1
LOCUSID
ALIAS
SOX25

Other Information

Locus ID:

NCBI: 11166
MIM: 604974
HGNC: 11197
Ensembl: ENSG00000125285

Variants:

dbSNP: 11166
ClinVar: 11166
TCGA: ENSG00000125285
COSMIC: SOX21

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000125285ENST00000376945Q9Y651

Expression (GTEx)

0
5
10
15
20
25
30

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
363353562022SOX21-AS1 activated by STAT6 promotes pancreatic cancer progression via up-regulation of SOX21.4
363618522022SOX2 and SOX21 in Lung Epithelial Differentiation and Repair.1
363353562022SOX21-AS1 activated by STAT6 promotes pancreatic cancer progression via up-regulation of SOX21.4
363618522022SOX2 and SOX21 in Lung Epithelial Differentiation and Repair.1
334025692021Quantitative detection of SRY-Box 21 (SOX21) gene promoter methylation as a stool-based noninvasive biomarker for early diagnosis of colorectal cancer by MethyLight method.3
342866932021SOX21 modulates SOX2-initiated differentiation of epithelial cells in the extrapulmonary airways.11
334025692021Quantitative detection of SRY-Box 21 (SOX21) gene promoter methylation as a stool-based noninvasive biomarker for early diagnosis of colorectal cancer by MethyLight method.3
342866932021SOX21 modulates SOX2-initiated differentiation of epithelial cells in the extrapulmonary airways.11
324453202020High potential of SOX21 gene promoter methylation as an epigenetic biomarker for early detection of colorectal cancer.3
324453202020High potential of SOX21 gene promoter methylation as an epigenetic biomarker for early detection of colorectal cancer.3
309923912019SOX21-AS1 is associated with clinical stage and regulates cell proliferation in nephroblastoma.16
317616772019SOX21 Ensures Rostral Forebrain Identity by Suppression of WNT8B during Neural Regionalization of Human Embryonic Stem Cells.5
309923912019SOX21-AS1 is associated with clinical stage and regulates cell proliferation in nephroblastoma.16
317616772019SOX21 Ensures Rostral Forebrain Identity by Suppression of WNT8B during Neural Regionalization of Human Embryonic Stem Cells.5
297724332018LncRNA SOX21-AS1 is associated with progression of hepatocellular carcinoma and predicts prognosis through epigenetically silencing p21.24

Citation

Dessen P

SOX21 (SRY-box transcription factor 21)

Atlas Genet Cytogenet Oncol Haematol. 2013-11-01

Online version: http://atlasgeneticsoncology.org/gene/53568/sox21-(sry-box-transcription-factor-21)