INSL5 (insulin like 5)

2013-11-01  

Identity

HGNC
LOCATION
1p31.3
LOCUSID
ALIAS
PRO182,UNQ156

Other Information

Locus ID:

NCBI: 10022
MIM: 606413
HGNC: 6088
Ensembl: ENSG00000172410

Variants:

dbSNP: 10022
ClinVar: 10022
TCGA: ENSG00000172410
COSMIC: INSL5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172410ENST00000304526Q9Y5Q6

Expression (GTEx)

0
1

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
Peptide ligand-binding receptorsREACTOMER-HSA-375276
Relaxin receptorsREACTOMER-HSA-444821
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (i) signalling eventsREACTOMER-HSA-418594

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
372075062023Insulin-like peptide 5 is associated with insulin resistance in women with polycystic ovary syndrome.0
372075062023Insulin-like peptide 5 is associated with insulin resistance in women with polycystic ovary syndrome.0
363032312022Insulin-like peptide 5 (INSL5) positively correlates with anti-Müllerian hormone (AMH) in women with the polycystic ovary syndrome: a case-control study.0
363032312022Insulin-like peptide 5 (INSL5) positively correlates with anti-Müllerian hormone (AMH) in women with the polycystic ovary syndrome: a case-control study.0
346808722021Expression of Cytokine-Coding Genes BMP8B, LEFTY1 and INSL5 Could Distinguish between Ulcerative Colitis and Crohn's Disease.2
346808722021Expression of Cytokine-Coding Genes BMP8B, LEFTY1 and INSL5 Could Distinguish between Ulcerative Colitis and Crohn's Disease.2
326570282020Autocrine INSL5 promotes tumor progression and glycolysis via activation of STAT5 signaling.11
326570282020Autocrine INSL5 promotes tumor progression and glycolysis via activation of STAT5 signaling.11
299562142019Circulating insulin-like peptide 5 levels and its association with metabolic and hormonal parameters in women with polycystic ovary syndrome.5
299562142019Circulating insulin-like peptide 5 levels and its association with metabolic and hormonal parameters in women with polycystic ovary syndrome.5
294666172018Synthesis and Characterization of the R27S Genetic Variant of Insulin-like Peptide 5.0
295351832018INSL5 activates multiple signalling pathways and regulates GLP-1 secretion in NCI-H716 cells.6
294666172018Synthesis and Characterization of the R27S Genetic Variant of Insulin-like Peptide 5.0
295351832018INSL5 activates multiple signalling pathways and regulates GLP-1 secretion in NCI-H716 cells.6
282746162017Interaction mechanism of insulin-like peptide 5 with relaxin family peptide receptor 4.4

Citation

Dessen P

INSL5 (insulin like 5)

Atlas Genet Cytogenet Oncol Haematol. 2013-11-01

Online version: http://atlasgeneticsoncology.org/gene/53569/insl5-(insulin-like-5)