Identity
HGNC
LOCATION
15q26.1
LOCUSID
ALIAS
FPLD4,PERI,PLIN
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5346
MIM: 170290
HGNC: 9076
Ensembl: ENSG00000166819
Variants:
dbSNP: 5346
ClinVar: 5346
TCGA: ENSG00000166819
COSMIC: PLIN1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000166819 | ENST00000300055 | O60240 |
| ENSG00000166819 | ENST00000430628 | O60240 |
| ENSG00000166819 | ENST00000560330 | H0YM16 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA128406954 | Weight gain | Disease | ClinicalAnnotation | associated | PD | 16732015 | |
| PA443890 | Diabetes Mellitus, Type 2 | Disease | ClinicalAnnotation | associated | PD | 16732015 | |
| PA451283 | rosiglitazone | Chemical | ClinicalAnnotation | associated | PD | 16732015 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38214891 | 2024 | Perilipin 1: a systematic review on its functions on lipid metabolism and atherosclerosis in mice and humans. | 1 |
| 38453058 | 2024 | Correlational analysis of PLIN1 with inflammation in diabetic foot ulcer wounds. | 0 |
| 38214891 | 2024 | Perilipin 1: a systematic review on its functions on lipid metabolism and atherosclerosis in mice and humans. | 1 |
| 38453058 | 2024 | Correlational analysis of PLIN1 with inflammation in diabetic foot ulcer wounds. | 0 |
| 35662076 | 2023 | Lipid Droplet Protein PLIN1 Regulates Inflammatory Polarity in Human Macrophages and is Involved in Atherosclerotic Plaque Development by Promoting Stable Lipid Storage. | 3 |
| 35709010 | 2023 | Autoantibodies to Perilipin-1 Define a Subset of Acquired Generalized Lipodystrophy. | 12 |
| 37368137 | 2023 | Effect of an acute long-duration exercise bout on skeletal muscle lipid droplet morphology, GLUT 4 protein, and perilipin protein expression. | 2 |
| 37843309 | 2023 | RS2289487 variation in PERILIPIN gene is a predictor of weight loss and protection against impaired glucose metabolism after a meal-replacement diet in postmenopausal obese females. | 0 |
| 35662076 | 2023 | Lipid Droplet Protein PLIN1 Regulates Inflammatory Polarity in Human Macrophages and is Involved in Atherosclerotic Plaque Development by Promoting Stable Lipid Storage. | 3 |
| 35709010 | 2023 | Autoantibodies to Perilipin-1 Define a Subset of Acquired Generalized Lipodystrophy. | 12 |
| 37368137 | 2023 | Effect of an acute long-duration exercise bout on skeletal muscle lipid droplet morphology, GLUT 4 protein, and perilipin protein expression. | 2 |
| 37843309 | 2023 | RS2289487 variation in PERILIPIN gene is a predictor of weight loss and protection against impaired glucose metabolism after a meal-replacement diet in postmenopausal obese females. | 0 |
| 34627746 | 2022 | Aquaglyceroporins and orthodox aquaporins in human adipocytes. | 9 |
| 34725012 | 2022 | Polymorphism PLIN1 11482 G>A interacts with dietary intake to modulate anthropometric measures and lipid profile in adults with normal-weight obesity syndrome. | 4 |
| 35235652 | 2022 | PLIN1 Haploinsufficiency Causes a Favorable Metabolic Profile. | 4 |
Citation
Dessen P
PLIN1 (perilipin 1)
Atlas Genet Cytogenet Oncol Haematol. 2013-11-01
Online version: http://atlasgeneticsoncology.org/gene/53570/plin1-(perilipin-1)
