Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 116447
MIM: 606387
HGNC: 29787
Ensembl: ENSG00000184428
Variants:
dbSNP: 116447
ClinVar: 116447
TCGA: ENSG00000184428
COSMIC: TOP1MT
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37923603 | 2024 | Association of TOP1MT with immune infiltration and checkpoint in colorectal cance. | 0 |
| 37923603 | 2024 | Association of TOP1MT with immune infiltration and checkpoint in colorectal cance. | 0 |
| 37129502 | 2023 | Activation of the cGAS-STING innate immune response in cells with deficient mitochondrial topoisomerase TOP1MT. | 5 |
| 37129502 | 2023 | Activation of the cGAS-STING innate immune response in cells with deficient mitochondrial topoisomerase TOP1MT. | 5 |
| 36030054 | 2022 | Functional characterization of two variants of mitochondrial topoisomerase TOP1MT that impact regulation of the mitochondrial genome. | 4 |
| 36215039 | 2022 | Two type I topoisomerases maintain DNA topology in human mitochondria. | 6 |
| 36030054 | 2022 | Functional characterization of two variants of mitochondrial topoisomerase TOP1MT that impact regulation of the mitochondrial genome. | 4 |
| 36215039 | 2022 | Two type I topoisomerases maintain DNA topology in human mitochondria. | 6 |
| 30622257 | 2019 | The mitochondrial type IB topoisomerase drives mitochondrial translation and carcinogenesis. | 26 |
| 30622257 | 2019 | The mitochondrial type IB topoisomerase drives mitochondrial translation and carcinogenesis. | 26 |
| 28874393 | 2017 | TOP1MT deficiency promotes GC invasion and migration via the enhancements of LDHA expression and aerobic glycolysis. | 14 |
| 28874393 | 2017 | TOP1MT deficiency promotes GC invasion and migration via the enhancements of LDHA expression and aerobic glycolysis. | 14 |
| 24172750 | 2014 | Effect of oxindolimine copper(II) and zinc(II) complexes on human topoisomerase I activity. | 4 |
| 24172750 | 2014 | Effect of oxindolimine copper(II) and zinc(II) complexes on human topoisomerase I activity. | 4 |
| 23261817 | 2013 | Collaborating functions of BLM and DNA topoisomerase I in regulating human rDNA transcription. | 24 |
Citation
Dessen P
TOP1MT (DNA topoisomerase I mitochondrial)
Atlas Genet Cytogenet Oncol Haematol. 2013-11-01
Online version: http://atlasgeneticsoncology.org/gene/53578/top1mt-(dna-topoisomerase-i-mitochondrial)
