Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 619373
MIM: 611940
HGNC: 32311
Ensembl: ENSG00000177669
Variants:
dbSNP: 619373
ClinVar: 619373
TCGA: ENSG00000177669
COSMIC: MBOAT4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000177669 | ENST00000320542 | Q96T53 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Metabolism of proteins | REACTOME | R-HSA-392499 |
| Peptide hormone metabolism | REACTOME | R-HSA-2980736 |
| Synthesis, secretion, and deacylation of Ghrelin | REACTOME | R-HSA-422085 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38341037 | 2024 | Anorexia of ageing is associated with elevated fasted and lower post-prandial ghrelin, independent of ghrelin O-acyltransferase. | 0 |
| 38341037 | 2024 | Anorexia of ageing is associated with elevated fasted and lower post-prandial ghrelin, independent of ghrelin O-acyltransferase. | 0 |
| 33103129 | 2020 | Unacylated-Ghrelin Impairs Hippocampal Neurogenesis and Memory in Mice and Is Altered in Parkinson's Dementia in Humans. | 11 |
| 33103129 | 2020 | Unacylated-Ghrelin Impairs Hippocampal Neurogenesis and Memory in Mice and Is Altered in Parkinson's Dementia in Humans. | 11 |
| 30597386 | 2019 | Differential expression of the ghrelin-related mRNAs GHS-R1a, GHS-R1b, and MBOAT4 in Japanese patients with schizophrenia. | 1 |
| 30597386 | 2019 | Differential expression of the ghrelin-related mRNAs GHS-R1a, GHS-R1b, and MBOAT4 in Japanese patients with schizophrenia. | 1 |
| 28846466 | 2018 | Identification and Characterization of a New Series of Ghrelin O-Acyl Transferase Inhibitors. | 7 |
| 30256519 | 2018 | Plasma ghrelin O-acyltransferase (GOAT) enzyme levels: A novel non-invasive diagnosis tool for patients with significant prostate cancer. | 10 |
| 30297816 | 2018 | Ghrelin-O-Acyltransferase (GOAT) Enzyme as a Novel Potential Biomarker in Gastroenteropancreatic Neuroendocrine Tumors. | 6 |
| 28846466 | 2018 | Identification and Characterization of a New Series of Ghrelin O-Acyl Transferase Inhibitors. | 7 |
| 30256519 | 2018 | Plasma ghrelin O-acyltransferase (GOAT) enzyme levels: A novel non-invasive diagnosis tool for patients with significant prostate cancer. | 10 |
| 30297816 | 2018 | Ghrelin-O-Acyltransferase (GOAT) Enzyme as a Novel Potential Biomarker in Gastroenteropancreatic Neuroendocrine Tumors. | 6 |
| 28134508 | 2017 | Synthetic Triterpenoid Inhibition of Human Ghrelin O-Acyltransferase: The Involvement of a Functionally Required Cysteine Provides Mechanistic Insight into Ghrelin Acylation. | 11 |
| 28134508 | 2017 | Synthetic Triterpenoid Inhibition of Human Ghrelin O-Acyltransferase: The Involvement of a Functionally Required Cysteine Provides Mechanistic Insight into Ghrelin Acylation. | 11 |
| 27489223 | 2016 | Ghrelin O-acyltransferase (GOAT), a specific enzyme that modifies ghrelin with a medium-chain fatty acid. | 7 |
Citation
Dessen P
MBOAT4 (membrane bound O-acyltransferase domain containing 4)
Atlas Genet Cytogenet Oncol Haematol. 2013-11-01
Online version: http://atlasgeneticsoncology.org/gene/53584/mboat4-(membrane-bound-o-acyltransferase-domain-containing-4)
