Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 117194
MIM: 607228
HGNC: 17983
Ensembl: ENSG00000183695
Variants:
dbSNP: 117194
ClinVar: 117194
TCGA: ENSG00000183695
COSMIC: MRGPRX2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000183695 | ENST00000329773 | Q96LB1 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38184723 | 2024 | Proinflammatory chemokine CXCL14 activates MAS-related G protein-coupled receptor MRGPRX2 and its putative mouse ortholog MRGPRB2. | 0 |
| 38334612 | 2024 | Beyond Allergies-Updates on The Role of Mas-Related G-Protein-Coupled Receptor X2 in Chronic Urticaria and Atopic Dermatitis. | 0 |
| 38184723 | 2024 | Proinflammatory chemokine CXCL14 activates MAS-related G protein-coupled receptor MRGPRX2 and its putative mouse ortholog MRGPRB2. | 0 |
| 38334612 | 2024 | Beyond Allergies-Updates on The Role of Mas-Related G-Protein-Coupled Receptor X2 in Chronic Urticaria and Atopic Dermatitis. | 0 |
| 37228611 | 2023 | Substance P analogs devoid of key residues fail to activate human mast cells via MRGPRX2. | 2 |
| 37516794 | 2023 | PACAP activates MRGPRX2 on meningeal mast cells to drive migraine-like pain. | 4 |
| 37875175 | 2023 | miR-212/132 attenuates OVA-induced airway inflammation by inhibiting mast cells activation through MRGPRX2 and ASAP1. | 0 |
| 37228611 | 2023 | Substance P analogs devoid of key residues fail to activate human mast cells via MRGPRX2. | 2 |
| 37516794 | 2023 | PACAP activates MRGPRX2 on meningeal mast cells to drive migraine-like pain. | 4 |
| 37875175 | 2023 | miR-212/132 attenuates OVA-induced airway inflammation by inhibiting mast cells activation through MRGPRX2 and ASAP1. | 0 |
| 34329659 | 2022 | Cytokine Stimulation by MRGPRX2 Occurs with Lower Potency than by FcεRI Aggregation but with Similar Dependence on the Extracellular Signal-Regulated Kinase 1/2 Module in Human Skin Mast Cells. | 6 |
| 34861349 | 2022 | Synthesis of unnatural morphinan compounds to induce itch-like behaviors in mice: Towards the development of MRGPRX2 selective ligands. | 1 |
| 34920312 | 2022 | MrgprX2 regulates mast cell degranulation through PI3K/AKT and PLCγ signaling in pseudo-allergic reactions. | 11 |
| 35065236 | 2022 | Synthesis and evaluation of new potential anti-pseudo-allergic agents. | 0 |
| 35283140 | 2022 | Mast cells, cortistatin, and its receptor, MRGPRX2, are linked to the pathogenesis of chronic prurigo. | 20 |
Citation
Dessen P
MRGPRX2 (MAS related GPR family member X2)
Atlas Genet Cytogenet Oncol Haematol. 2013-11-01
Online version: http://atlasgeneticsoncology.org/gene/53587/mrgprx2-(mas-related-gpr-family-member-x2)
