Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 80237
MIM: 609885
HGNC: 23113
Ensembl: ENSG00000128886
Variants:
dbSNP: 80237
ClinVar: 80237
TCGA: ENSG00000128886
COSMIC: ELL3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000128886 | ENST00000319359 | Q9HB65 |
| ENSG00000128886 | ENST00000433927 | C9JHD8 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| RNA polymerase II transcribes snRNA genes | REACTOME | R-HSA-6807505 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30654843 | 2019 | Ell3 functions as a critical decision maker at the crossroad between stem cell senescence and apoptosis. | 0 |
| 30654843 | 2019 | Ell3 functions as a critical decision maker at the crossroad between stem cell senescence and apoptosis. | 0 |
| 28514748 | 2017 | A transcriptional complex composed of ER(α), GATA3, FOXA1 and ELL3 regulates IL-20 expression in breast cancer cells. | 6 |
| 28858629 | 2017 | Selective expression of the transcription elongation factor ELL3 in B cells prior to ELL2 drives proliferation and survival. | 8 |
| 28514748 | 2017 | A transcriptional complex composed of ER(α), GATA3, FOXA1 and ELL3 regulates IL-20 expression in breast cancer cells. | 6 |
| 28858629 | 2017 | Selective expression of the transcription elongation factor ELL3 in B cells prior to ELL2 drives proliferation and survival. | 8 |
| 26540344 | 2015 | Ell3 stabilizes p53 following CDDP treatment via its effects on ubiquitin-dependent and -independent proteasomal degradation pathways in breast cancer cells. | 9 |
| 26540344 | 2015 | Ell3 stabilizes p53 following CDDP treatment via its effects on ubiquitin-dependent and -independent proteasomal degradation pathways in breast cancer cells. | 9 |
| 23850691 | 2013 | Ell3 stimulates proliferation, drug resistance, and cancer stem cell properties of breast cancer cells via a MEK/ERK-dependent signaling pathway. | 14 |
| 23850691 | 2013 | Ell3 stimulates proliferation, drug resistance, and cancer stem cell properties of breast cancer cells via a MEK/ERK-dependent signaling pathway. | 14 |
Citation
Dessen P
ELL3 (elongation factor for RNA polymerase II 3)
Atlas Genet Cytogenet Oncol Haematol. 2013-11-01
Online version: http://atlasgeneticsoncology.org/gene/53595/cancer-prone-explorer/
