Identity
HGNC
LOCATION
3p21.1
LOCUSID
ALIAS
GP120,H4P,IHRP,ITI-HC4,ITIHL1,PK-120,PK120
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3700
MIM: 600564
HGNC: 6169
Ensembl: ENSG00000055955
Variants:
dbSNP: 3700
ClinVar: 3700
TCGA: ENSG00000055955
COSMIC: ITIH4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000055955 | ENST00000266041 | Q14624 |
| ENSG00000055955 | ENST00000406595 | Q14624 |
| ENSG00000055955 | ENST00000441637 | H7C0L5 |
| ENSG00000055955 | ENST00000485816 | B7ZKJ8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38289873 | 2024 | Translatome profiling reveals Itih4 as a novel smooth muscle cell-specific gene in atherosclerosis. | 0 |
| 38289873 | 2024 | Translatome profiling reveals Itih4 as a novel smooth muscle cell-specific gene in atherosclerosis. | 0 |
| 36725250 | 2023 | Longitudinal change of serum inter-alpha-trypsin inhibitor heavy chain H4, and its correlation with inflammation, multiorgan injury, and death risk in sepsis. | 3 |
| 36841032 | 2023 | PGK1 modulates balance between pro- and anti-inflammatory cytokines by interacting with ITI-H4. | 2 |
| 37335061 | 2023 | Hyperglycosylated N-Linked Site 339 of gp120 Appears to Be Unique and May Contribute to CRF01_AE Transmission Among Men Who Have Sex with Men in China and Thailand. | 0 |
| 38156824 | 2023 | Serum interα-trypsin inhibitor heavy chain H4 may be an anti-inflammatory marker reflecting disease risk, activity and treatment outcome of ankylosing spondylitis. | 0 |
| 36725250 | 2023 | Longitudinal change of serum inter-alpha-trypsin inhibitor heavy chain H4, and its correlation with inflammation, multiorgan injury, and death risk in sepsis. | 3 |
| 36841032 | 2023 | PGK1 modulates balance between pro- and anti-inflammatory cytokines by interacting with ITI-H4. | 2 |
| 37335061 | 2023 | Hyperglycosylated N-Linked Site 339 of gp120 Appears to Be Unique and May Contribute to CRF01_AE Transmission Among Men Who Have Sex with Men in China and Thailand. | 0 |
| 38156824 | 2023 | Serum interα-trypsin inhibitor heavy chain H4 may be an anti-inflammatory marker reflecting disease risk, activity and treatment outcome of ankylosing spondylitis. | 0 |
| 34247200 | 2022 | Associations between KCNQ1 and ITIH4 gene polymorphisms and infant weight gain in early life. | 0 |
| 36891881 | 2022 | Serum ITIH4 in coronary heart disease: a potential anti-inflammatory biomarker related to stenosis degree and risk of major adverse cardiovascular events. | 3 |
| 34247200 | 2022 | Associations between KCNQ1 and ITIH4 gene polymorphisms and infant weight gain in early life. | 0 |
| 36891881 | 2022 | Serum ITIH4 in coronary heart disease: a potential anti-inflammatory biomarker related to stenosis degree and risk of major adverse cardiovascular events. | 3 |
| 33238047 | 2021 | Citrullinated inter-alpha-trypsin inhibitor heavy chain 4 in arthritic joints and its potential effect in the neutrophil migration. | 5 |
Citation
Dessen P
ITIH4 (inter-alpha-trypsin inhibitor heavy chain 4)
Atlas Genet Cytogenet Oncol Haematol. 2013-11-01
Online version: http://atlasgeneticsoncology.org/gene/53598/itih4-(inter-alpha-trypsin-inhibitor-heavy-chain-4)
