Identity
HGNC
LOCATION
2q11.2
LOCUSID
ALIAS
M-SEMA-F,SEMACL1,SEMAF,SEMAI
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54910
MIM: 604462
HGNC: 10731
Ensembl: ENSG00000168758
Variants:
dbSNP: 54910
ClinVar: 54910
TCGA: ENSG00000168758
COSMIC: SEMA4C
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000168758 | ENST00000305476 | Q9C0C4 |
| ENSG00000168758 | ENST00000442264 | C9JV89 |
| ENSG00000168758 | ENST00000449330 | C9J4M7 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Axon guidance | KEGG | ko04360 |
| Axon guidance | KEGG | hsa04360 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34459126 | 2021 | Serum semaphorin4C as an auxiliary diagnostic biomarker for breast cancer. | 0 |
| 34747314 | 2021 | Effect of microrna-138 on epithelial-Mesenchymal transition and invasion of breast cancer cells by targeting semaphorin 4C. | 1 |
| 34459126 | 2021 | Serum semaphorin4C as an auxiliary diagnostic biomarker for breast cancer. | 0 |
| 34747314 | 2021 | Effect of microrna-138 on epithelial-Mesenchymal transition and invasion of breast cancer cells by targeting semaphorin 4C. | 1 |
| 31582836 | 2020 | SEMA4C is a novel target to limit osteosarcoma growth, progression, and metastasis. | 6 |
| 31951596 | 2020 | Downregulation of SEMA4C Inhibit Epithelial-Mesenchymal Transition (EMT) and the Invasion and Metastasis of Cervical Cancer Cells via Inhibiting Transforming Growth Factor-beta 1 (TGF-β1)-Induced Hela cells p38 Mitogen-Activated Protein Kinase (MAPK) Activation. | 11 |
| 32244055 | 2020 | Semaphorin 4A, 4C, and 4D: Function comparison in the autoimmunity, allergy, and cancer. | 14 |
| 33177246 | 2020 | High SEMA4C expression promotes the epithelial-mesenchymal transition and predicts poor prognosis in colorectal carcinoma. | 9 |
| 31582836 | 2020 | SEMA4C is a novel target to limit osteosarcoma growth, progression, and metastasis. | 6 |
| 31951596 | 2020 | Downregulation of SEMA4C Inhibit Epithelial-Mesenchymal Transition (EMT) and the Invasion and Metastasis of Cervical Cancer Cells via Inhibiting Transforming Growth Factor-beta 1 (TGF-β1)-Induced Hela cells p38 Mitogen-Activated Protein Kinase (MAPK) Activation. | 11 |
| 32244055 | 2020 | Semaphorin 4A, 4C, and 4D: Function comparison in the autoimmunity, allergy, and cancer. | 14 |
| 33177246 | 2020 | High SEMA4C expression promotes the epithelial-mesenchymal transition and predicts poor prognosis in colorectal carcinoma. | 9 |
| 31308149 | 2019 | Semaphorin 4C Promotes Macrophage Recruitment and Angiogenesis in Breast Cancer. | 18 |
| 31776419 | 2019 | Sema4C mediates EMT inducing chemotherapeutic resistance of miR-31-3p in cervical cancer cells. | 16 |
| 31308149 | 2019 | Semaphorin 4C Promotes Macrophage Recruitment and Angiogenesis in Breast Cancer. | 18 |
Citation
Dessen P
SEMA4C (semaphorin 4C)
Atlas Genet Cytogenet Oncol Haematol. 2013-11-01
Online version: http://atlasgeneticsoncology.org/gene/53606/sema4c-(semaphorin-4c)
