Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 120227
MIM: 608713
HGNC: 20580
Ensembl: ENSG00000186104
Variants:
dbSNP: 120227
ClinVar: 120227
TCGA: ENSG00000186104
COSMIC: CYP2R1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164745614 | calcidiol | Chemical | MultilinkAnnotation | associated | 26661839 | ||
| PA164784024 | peginterferon alfa-2b | Chemical | ClinicalAnnotation | associated | PD | ||
| PA446863 | Hepatitis C, Chronic | Disease | ClinicalAnnotation | associated | PD | ||
| PA451241 | ribavirin | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38632160 | 2024 | Gene expression profiling of vitamin D metabolism enzymes in leukemia and lymphoma patients: molecular aspect interplay of VDR, CYP2R1, and CYP24A1. | 1 |
| 38732523 | 2024 | Relationship between Vitamin D3 Deficiency, Metabolic Syndrome and VDR, GC, and CYP2R1 Gene Polymorphisms. | 1 |
| 38632160 | 2024 | Gene expression profiling of vitamin D metabolism enzymes in leukemia and lymphoma patients: molecular aspect interplay of VDR, CYP2R1, and CYP24A1. | 1 |
| 38732523 | 2024 | Relationship between Vitamin D3 Deficiency, Metabolic Syndrome and VDR, GC, and CYP2R1 Gene Polymorphisms. | 1 |
| 37495756 | 2023 | Biomarkers of ulcerative colitis disease activity CXCL1, CYP2R1, LPCAT1, and NEU4 and their relationship to immune infiltrates. | 0 |
| 37675692 | 2023 | Correlation of CYP2R1 gene promoter methylation with circulating vitamin D levels among healthy adults. | 0 |
| 37898838 | 2023 | Association of Single Nucleotide Polymorphism in VDR, GC Globulin and CYP2R1 with the Risk of Esophageal Cancer. | 0 |
| 37929021 | 2023 | Single nucleotide polymorphisms in vitamin D binding protein and 25-hydroxylase genes affect vitamin D levels in adolescents of Arab ethnicity in Kuwait. | 1 |
| 37495756 | 2023 | Biomarkers of ulcerative colitis disease activity CXCL1, CYP2R1, LPCAT1, and NEU4 and their relationship to immune infiltrates. | 0 |
| 37675692 | 2023 | Correlation of CYP2R1 gene promoter methylation with circulating vitamin D levels among healthy adults. | 0 |
| 37898838 | 2023 | Association of Single Nucleotide Polymorphism in VDR, GC Globulin and CYP2R1 with the Risk of Esophageal Cancer. | 0 |
| 37929021 | 2023 | Single nucleotide polymorphisms in vitamin D binding protein and 25-hydroxylase genes affect vitamin D levels in adolescents of Arab ethnicity in Kuwait. | 1 |
| 32938288 | 2022 | Genetic variants of vitamin D metabolism-related DHCR7/NADSYN1 locus and CYP2R1 gene are associated with clinical features of Parkinson's disease. | 2 |
| 34906413 | 2022 | The influence of CYP2R1 polymorphisms and gene-obesity interaction with hypertension risk in a Chinese rural population. | 1 |
| 35057442 | 2022 | Haplotypes in the GC, CYP2R1 and CYP24A1 Genes and Biomarkers of Bone Mineral Metabolism in Older Adults. | 0 |
Citation
Dessen P
CYP2R1 (cytochrome P450 family 2 subfamily R member 1)
Atlas Genet Cytogenet Oncol Haematol. 2013-11-01
Online version: http://atlasgeneticsoncology.org/gene/53609/cyp2r1-(cytochrome-p450-family-2-subfamily-r-member-1)
