Identity
HGNC
LOCATION
3q12.3
LOCUSID
ALIAS
IKBZ,INAP,MAIL
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64332
MIM: 608004
HGNC: 29805
Ensembl: ENSG00000144802
Variants:
dbSNP: 64332
ClinVar: 64332
TCGA: ENSG00000144802
COSMIC: NFKBIZ
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Transcriptional misregulation in cancer | KEGG | ko05202 |
| Transcriptional misregulation in cancer | KEGG | hsa05202 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38581570 | 2024 | NFKBIZ regulates NFκB signaling pathway to mediate tumorigenesis and metastasis of hepatocellular carcinoma by direct interaction with TRIM16. | 0 |
| 38960718 | 2024 | Structural and biochemical analyses of the nuclear IκBζ protein in complex with the NF-κB p50 homodimer. | 1 |
| 38581570 | 2024 | NFKBIZ regulates NFκB signaling pathway to mediate tumorigenesis and metastasis of hepatocellular carcinoma by direct interaction with TRIM16. | 0 |
| 38960718 | 2024 | Structural and biochemical analyses of the nuclear IκBζ protein in complex with the NF-κB p50 homodimer. | 1 |
| 37725983 | 2023 | IκBζ is an essential mediator of immunity to oropharyngeal candidiasis. | 1 |
| 37725983 | 2023 | IκBζ is an essential mediator of immunity to oropharyngeal candidiasis. | 1 |
| 35148999 | 2022 | PFN1 Prevents Psoriasis Pathogenesis through IκBζ Regulation. | 5 |
| 35777990 | 2022 | Genetic variants in the NF-κB signaling pathway (NFKB1, NFKBIA, NFKBIZ) and risk of critical outcome among COVID-19 patients. | 5 |
| 36245291 | 2022 | Emerging role of IκBζ in inflammation: Emphasis on psoriasis. | 3 |
| 35148999 | 2022 | PFN1 Prevents Psoriasis Pathogenesis through IκBζ Regulation. | 5 |
| 35777990 | 2022 | Genetic variants in the NF-κB signaling pathway (NFKB1, NFKBIA, NFKBIZ) and risk of critical outcome among COVID-19 patients. | 5 |
| 36245291 | 2022 | Emerging role of IκBζ in inflammation: Emphasis on psoriasis. | 3 |
| 33491092 | 2021 | IkBζ is a Key Regulator of Tumour Necrosis Factor-a and Interleukin-17A-mediated Induction of Interleukin-36g in Human Keratinocytes. | 4 |
| 33907827 | 2021 | Upregulation of NFKBIZ affects bladder cancer progression via the PTEN/PI3K/Akt signaling pathway. | 9 |
| 33491092 | 2021 | IkBζ is a Key Regulator of Tumour Necrosis Factor-a and Interleukin-17A-mediated Induction of Interleukin-36g in Human Keratinocytes. | 4 |
Citation
Dessen P
NFKBIZ (NFKB inhibitor zeta)
Atlas Genet Cytogenet Oncol Haematol. 2013-11-01
Online version: http://atlasgeneticsoncology.org/gene/53613/
