Identity
HGNC
LOCATION
16q12.1
LOCUSID
ALIAS
Ebfaz,JBTS19,NPHP14,OAZ,Roaz,ZFP423,Zfp104,hOAZ
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23090
MIM: 604557
HGNC: 16762
Ensembl: ENSG00000102935
Variants:
dbSNP: 23090
ClinVar: 23090
TCGA: ENSG00000102935
COSMIC: ZNF423
RNA/Proteins
Expression (GTEx)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443560 | Breast Neoplasms | Disease | ClinicalAnnotation | associated | PD | 23764426 | |
| PA451221 | raloxifene | Chemical | ClinicalAnnotation | associated | PD | 23764426 | |
| PA451581 | tamoxifen | Chemical | ClinicalAnnotation | associated | PD | 23764426 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35313831 | 2022 | Expression of the preadipocyte marker ZFP423 is dysregulated between well-differentiated and dedifferentiated liposarcoma. | 2 |
| 35313831 | 2022 | Expression of the preadipocyte marker ZFP423 is dysregulated between well-differentiated and dedifferentiated liposarcoma. | 2 |
| 32925911 | 2020 | ZNF423 patient variants, truncations, and in-frame deletions in mice define an allele-dependent range of midline brain abnormalities. | 5 |
| 32925911 | 2020 | ZNF423 patient variants, truncations, and in-frame deletions in mice define an allele-dependent range of midline brain abnormalities. | 5 |
| 31283791 | 2019 | Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease. | 16 |
| 31284679 | 2019 | Roles of Zinc Finger Protein 423 in Proliferation and Invasion of Cholangiocarcinoma through Oxidative Stress. | 7 |
| 31283791 | 2019 | Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease. | 16 |
| 31284679 | 2019 | Roles of Zinc Finger Protein 423 in Proliferation and Invasion of Cholangiocarcinoma through Oxidative Stress. | 7 |
| 28821270 | 2017 | Calmodulin-like protein 3 is an estrogen receptor alpha coregulator for gene expression and drug response in a SNP, estrogen, and SERM-dependent fashion. | 13 |
| 28968398 | 2017 | SNPs near the cysteine proteinase cathepsin O gene (CTSO) determine tamoxifen sensitivity in ERα-positive breast cancer through regulation of BRCA1. | 15 |
| 28821270 | 2017 | Calmodulin-like protein 3 is an estrogen receptor alpha coregulator for gene expression and drug response in a SNP, estrogen, and SERM-dependent fashion. | 13 |
| 28968398 | 2017 | SNPs near the cysteine proteinase cathepsin O gene (CTSO) determine tamoxifen sensitivity in ERα-positive breast cancer through regulation of BRCA1. | 15 |
| 26788497 | 2015 | ZNF423 and ZNF521: EBF1 Antagonists of Potential Relevance in B-Lymphoid Malignancies. | 19 |
| 26788497 | 2015 | ZNF423 and ZNF521: EBF1 Antagonists of Potential Relevance in B-Lymphoid Malignancies. | 19 |
| 25219468 | 2014 | Restored immunosuppressive effect of mesenchymal stem cells on B cells after olfactory 1/early B cell factor-associated zinc-finger protein down-regulation in patients with systemic lupus erythematosus. | 22 |
Citation
Dessen P
ZNF423 (zinc finger protein 423)
Atlas Genet Cytogenet Oncol Haematol. 2013-11-01
Online version: http://atlasgeneticsoncology.org/gene/53614/znf423-(zinc-finger-protein-423)
