Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2220
MIM: 601624
HGNC: 3624
Ensembl: ENSG00000160339
Variants:
dbSNP: 2220
ClinVar: 2220
TCGA: ENSG00000160339
COSMIC: FCN2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000160339 | ENST00000291744 | Q15485 |
| ENSG00000160339 | ENST00000350339 | Q15485 |
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10066 | duloxetine | Chemical | ClinicalAnnotation, VariantAnnotation | associated | PD | 29407288 | |
| PA447321 | Depressive Disorder, Major | Disease | ClinicalAnnotation, VariantAnnotation | associated | PD | 29407288 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36805857 | 2023 | l-ficolin-MASP arm of the complement system in schizophrenia. | 1 |
| 36833169 | 2023 | Selected SNPs of FCN2 Associated with Chronic Tonsillitis in the Polish Adult Population. | 0 |
| 38033168 | 2023 | Variants of IL6, IL10, FCN2, RNASE3, IL12B and IL17B loci are associated with Schistosoma mansoni worm burden in the Albert Nile region of Uganda. | 0 |
| 36805857 | 2023 | l-ficolin-MASP arm of the complement system in schizophrenia. | 1 |
| 36833169 | 2023 | Selected SNPs of FCN2 Associated with Chronic Tonsillitis in the Polish Adult Population. | 0 |
| 38033168 | 2023 | Variants of IL6, IL10, FCN2, RNASE3, IL12B and IL17B loci are associated with Schistosoma mansoni worm burden in the Albert Nile region of Uganda. | 0 |
| 35269955 | 2022 | Ficolin-2 Plasma Level Assesses Liver Fibrosis in Non-Alcoholic Fatty Liver Disease. | 1 |
| 35418983 | 2022 | Ficolin-2 Lectin Complement Pathway Mediates Capsule-Specific Innate Immunity Against Invasive Pneumococcal Disease. | 2 |
| 36499663 | 2022 | Association of the FCN2 Gene Promoter Region Polymorphisms with Very Low Birthweight in Preterm Neonates. | 3 |
| 35269955 | 2022 | Ficolin-2 Plasma Level Assesses Liver Fibrosis in Non-Alcoholic Fatty Liver Disease. | 1 |
| 35418983 | 2022 | Ficolin-2 Lectin Complement Pathway Mediates Capsule-Specific Innate Immunity Against Invasive Pneumococcal Disease. | 2 |
| 36499663 | 2022 | Association of the FCN2 Gene Promoter Region Polymorphisms with Very Low Birthweight in Preterm Neonates. | 3 |
| 33513354 | 2021 | Ficolin-2 serum levels predict the occurrence of acute coronary syndrome in patients with severe carotid artery stenosis. | 6 |
| 34529517 | 2021 | Novel FCN2 Variants and Haplotypes are Associated with Rheumatic Heart Disease. | 1 |
| 33513354 | 2021 | Ficolin-2 serum levels predict the occurrence of acute coronary syndrome in patients with severe carotid artery stenosis. | 6 |
Citation
Dessen P
FCN2 (ficolin 2)
Atlas Genet Cytogenet Oncol Haematol. 2013-11-01
Online version: http://atlasgeneticsoncology.org/gene/53615/fcn2-(ficolin-2)
