SH3BP5 (SH3 domain binding protein 5)

2013-11-01  

Identity

HGNC
LOCATION
3p25.1
LOCUSID
ALIAS
SAB,SH3BP-5
FUSION GENES

Other Information

Locus ID:

NCBI: 9467
MIM: 605612
HGNC: 10827
Ensembl: ENSG00000131370

Variants:

dbSNP: 9467
ClinVar: 9467
TCGA: ENSG00000131370
COSMIC: SH3BP5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000131370ENST00000366391C9JK30
ENSG00000131370ENST00000383791O60239
ENSG00000131370ENST00000383791A0A024R2G6
ENSG00000131370ENST00000408919O60239
ENSG00000131370ENST00000408919A0A024R2J3
ENSG00000131370ENST00000412806C9J140
ENSG00000131370ENST00000417936C9JNW0
ENSG00000131370ENST00000426925O60239
ENSG00000131370ENST00000426925A0A024R2J3
ENSG00000131370ENST00000450625F8WDU8

Expression (GTEx)

0
10
20
30
40
50
60

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
381419062024METTL3 suppresses invasion of lung cancer via SH3BP5 m6A modification.0
381419062024METTL3 suppresses invasion of lung cancer via SH3BP5 m6A modification.0
347839862022Novel blood-based hypomethylation of SH3BP5 is associated with very early-stage lung adenocarcinoma.2
347839862022Novel blood-based hypomethylation of SH3BP5 is associated with very early-stage lung adenocarcinoma.2
341289582021Tankyrase regulates epithelial lumen formation via suppression of Rab11 GEFs.3
341289582021Tankyrase regulates epithelial lumen formation via suppression of Rab11 GEFs.3
320668092020trans-Fatty acids facilitate DNA damage-induced apoptosis through the mitochondrial JNK-Sab-ROS positive feedback loop.10
320668092020trans-Fatty acids facilitate DNA damage-induced apoptosis through the mitochondrial JNK-Sab-ROS positive feedback loop.10
315468312019Elevated SH3BP5 Correlates with Poor Outcome and Contributes to the Growth of Acute Myeloid Leukemia Cells.2
315468312019Elevated SH3BP5 Correlates with Poor Outcome and Contributes to the Growth of Acute Myeloid Leukemia Cells.2
303228862018Sab concentrations indicate chemotherapeutic susceptibility in ovarian cancer cell lines.9
303228862018Sab concentrations indicate chemotherapeutic susceptibility in ovarian cancer cell lines.9
267453402016REI/SH3BP5 protein family: New GEFs for Rab11.4
271848322016Expressions of SH3BP5, LMO3, and SNAP25 in diffuse large B-cell lymphoma cells and their association with clinical features.7
267453402016REI/SH3BP5 protein family: New GEFs for Rab11.4

Citation

Dessen P

SH3BP5 (SH3 domain binding protein 5)

Atlas Genet Cytogenet Oncol Haematol. 2013-11-01

Online version: http://atlasgeneticsoncology.org/gene/53619/sh3bp5-(sh3-domain-binding-protein-5)