ADGRL4 (adhesion G protein-coupled receptor L4)

2013-11-01  

Identity

HGNC
LOCATION
1p31.1
LOCUSID
ALIAS
ELTD1,ETL,KPG_003

Other Information

Locus ID:

NCBI: 64123
MIM: 616419
HGNC: 20822
Ensembl: ENSG00000162618

Variants:

dbSNP: 64123
ClinVar: 64123
TCGA: ENSG00000162618
COSMIC: ADGRL4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000162618ENST00000370742Q9HBW9
ENSG00000162618ENST00000401034B1AR72
ENSG00000162618ENST00000640664A0A1W2PP07
ENSG00000162618ENST00000655029A0A590UJX8
ENSG00000162618ENST00000656300A0A590UJ41
ENSG00000162618ENST00000656841A0A590UJX8
ENSG00000162618ENST00000659463A0A590UJS7
ENSG00000162618ENST00000661030A0A590UJX8
ENSG00000162618ENST00000662530A0A590UK74
ENSG00000162618ENST00000662640A0A590UK90
ENSG00000162618ENST00000662895A0A590UJU5
ENSG00000162618ENST00000671209A0A590UJN9

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
343470792022ELTD1 deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma.5
343470792022ELTD1 deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma.5
334308142021Adhesion G protein-coupled receptor, ELTD1, is a potential therapeutic target for retinoblastoma migration and invasion.5
338933262021Elevated expression of the adhesion GPCR ADGRL4/ELTD1 promotes endothelial sprouting angiogenesis without activating canonical GPCR signalling.7
343489932021ADGRL4/ELTD1 Expression in Breast Cancer Cells Induces Vascular Normalization and Immune Suppression.4
344213492021ELTD1 promotes invasion and metastasis by activating MMP2 in colorectal cancer.11
346819532021ELTD1 Activation Induces an Endothelial-EMT Transition to a Myofibroblast Phenotype.3
334308142021Adhesion G protein-coupled receptor, ELTD1, is a potential therapeutic target for retinoblastoma migration and invasion.5
338933262021Elevated expression of the adhesion GPCR ADGRL4/ELTD1 promotes endothelial sprouting angiogenesis without activating canonical GPCR signalling.7
343489932021ADGRL4/ELTD1 Expression in Breast Cancer Cells Induces Vascular Normalization and Immune Suppression.4
344213492021ELTD1 promotes invasion and metastasis by activating MMP2 in colorectal cancer.11
346819532021ELTD1 Activation Induces an Endothelial-EMT Transition to a Myofibroblast Phenotype.3
315548592019ELTD1 facilitates glioma proliferation, migration and invasion by activating JAK/STAT3/HIF-1α signaling axis.27
315548592019ELTD1 facilitates glioma proliferation, migration and invasion by activating JAK/STAT3/HIF-1α signaling axis.27
274169552017ELTD1, an effective anti-angiogenic target for gliomas: preclinical assessment in mouse GL261 and human G55 xenograft glioma models.23

Citation

Dessen P

ADGRL4 (adhesion G protein-coupled receptor L4)

Atlas Genet Cytogenet Oncol Haematol. 2013-11-01

Online version: http://atlasgeneticsoncology.org/gene/53620/haematological-explorer/