Identity
HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
C16orf73,SPGF22,gs129
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 254528
MIM: 617670
HGNC: 28569
Ensembl: ENSG00000162039
Variants:
dbSNP: 254528
ClinVar: 254528
TCGA: ENSG00000162039
COSMIC: MEIOB
RNA/Proteins
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36331299 | 2022 | Nuclear localization of human MEIOB requires its NLS in the OB domain and interaction with SPATA22. | 0 |
| 36331299 | 2022 | Nuclear localization of human MEIOB requires its NLS in the OB domain and interaction with SPATA22. | 0 |
| 33628586 | 2021 | The cancer-testis gene, MEIOB, sensitizes triple-negative breast cancer to PARP1 inhibitors by inducing homologous recombination deficiency. | 6 |
| 33812231 | 2021 | The meiosis-specific MEIOB-SPATA22 complex cooperates with RPA to form a compacted mixed MEIOB/SPATA22/RPA/ssDNA complex. | 9 |
| 34392356 | 2021 | Whole-exome sequencing of consanguineous families with infertile men and women identifies homologous mutations in SPATA22 and MEIOB. | 14 |
| 33628586 | 2021 | The cancer-testis gene, MEIOB, sensitizes triple-negative breast cancer to PARP1 inhibitors by inducing homologous recombination deficiency. | 6 |
| 33812231 | 2021 | The meiosis-specific MEIOB-SPATA22 complex cooperates with RPA to form a compacted mixed MEIOB/SPATA22/RPA/ssDNA complex. | 9 |
| 34392356 | 2021 | Whole-exome sequencing of consanguineous families with infertile men and women identifies homologous mutations in SPATA22 and MEIOB. | 14 |
| 33166385 | 2020 | The ssDNA-binding protein MEIOB acts as a dosage-sensitive regulator of meiotic recombination. | 8 |
| 33166385 | 2020 | The ssDNA-binding protein MEIOB acts as a dosage-sensitive regulator of meiotic recombination. | 8 |
| 30838384 | 2019 | A new MEIOB mutation is a recurrent cause for azoospermia and testicular meiotic arrest. | 27 |
| 31000419 | 2019 | A truncating MEIOB mutation responsible for familial primary ovarian insufficiency abolishes its interaction with its partner SPATA22 and their recruitment to DNA double-strand breaks. | 27 |
| 30838384 | 2019 | A new MEIOB mutation is a recurrent cause for azoospermia and testicular meiotic arrest. | 27 |
| 31000419 | 2019 | A truncating MEIOB mutation responsible for familial primary ovarian insufficiency abolishes its interaction with its partner SPATA22 and their recruitment to DNA double-strand breaks. | 27 |
| 24068956 | 2013 | MEIOB targets single-strand DNA and is necessary for meiotic recombination. | 65 |
Citation
Dessen P
MEIOB (meiosis specific with OB-fold)
Atlas Genet Cytogenet Oncol Haematol. 2013-12-01
Online version: http://atlasgeneticsoncology.org/gene/53635/meiob-(meiosis-specific-with-ob-fold)
