Identity
HGNC
LOCATION
2p25.3
LOCUSID
ALIAS
MRD39,NZF1,ZC2H2C2,ZC2HC4B,myT1-L
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23040
MIM: 613084
HGNC: 7623
Ensembl: ENSG00000186487
Variants:
dbSNP: 23040
ClinVar: 23040
TCGA: ENSG00000186487
COSMIC: MYT1L
RNA/Proteins
Expression (GTEx)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA448320 | allopurinol | Chemical | ClinicalAnnotation | associated | PD | 30924126 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36782060 | 2023 | MYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention. | 4 |
| 37188826 | 2023 | 2p25.3 microduplications involving MYT1L: further phenotypic characterization through an assessment of 16 new cases and a literature review. | 1 |
| 36782060 | 2023 | MYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention. | 4 |
| 37188826 | 2023 | 2p25.3 microduplications involving MYT1L: further phenotypic characterization through an assessment of 16 new cases and a literature review. | 1 |
| 34748075 | 2022 | MYT1L-associated neurodevelopmental disorder: description of 40 new cases and literature review of clinical and molecular aspects. | 8 |
| 34748075 | 2022 | MYT1L-associated neurodevelopmental disorder: description of 40 new cases and literature review of clinical and molecular aspects. | 8 |
| 33941792 | 2021 | A web-based survey on various symptoms of computer vision syndrome and the genetic understanding based on a multi-trait genome-wide association study. | 0 |
| 34946857 | 2021 | Co-Occurrence of Fragile X Syndrome with a Second Genetic Condition: Three Independent Cases of Double Diagnosis. | 3 |
| 33941792 | 2021 | A web-based survey on various symptoms of computer vision syndrome and the genetic understanding based on a multi-trait genome-wide association study. | 0 |
| 34946857 | 2021 | Co-Occurrence of Fragile X Syndrome with a Second Genetic Condition: Three Independent Cases of Double Diagnosis. | 3 |
| 32065501 | 2020 | Nine newly identified individuals refine the phenotype associated with MYT1L mutations. | 8 |
| 32267091 | 2020 | MYT1L: A systematic review of genetic variation encompassing schizophrenia and autism. | 12 |
| 32391601 | 2020 | The neuronal transcription factor Myt1L interacts via a conserved motif with the PAH1 domain of Sin3 to recruit the Sin3L/Rpd3L histone deacetylase complex. | 3 |
| 32065501 | 2020 | Nine newly identified individuals refine the phenotype associated with MYT1L mutations. | 8 |
| 32267091 | 2020 | MYT1L: A systematic review of genetic variation encompassing schizophrenia and autism. | 12 |
Citation
Dessen P
MYT1L (myelin transcription factor 1 like)
Atlas Genet Cytogenet Oncol Haematol. 2013-12-01
Online version: http://atlasgeneticsoncology.org/gene/53639/myt1l-(myelin-transcription-factor-1-like)
