Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9462
MIM: 606136
HGNC: 9874
Ensembl: ENSG00000075391
Variants:
dbSNP: 9462
ClinVar: 9462
TCGA: ENSG00000075391
COSMIC: RASAL2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000075391 | ENST00000367649 | Q9UJF2 |
| ENSG00000075391 | ENST00000433130 | H0Y638 |
| ENSG00000075391 | ENST00000462775 | Q9UJF2 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38159595 | 2024 | CAMSAP2 enhances lung cancer cell metastasis by mediating RASAL2 degradation. | 0 |
| 38453052 | 2024 | RAS protein activator-like 2 (RASAL2) initiates peritubular capillary rarefaction in hypoxic renal interstitial fibrosis. | 0 |
| 38159595 | 2024 | CAMSAP2 enhances lung cancer cell metastasis by mediating RASAL2 degradation. | 0 |
| 38453052 | 2024 | RAS protein activator-like 2 (RASAL2) initiates peritubular capillary rarefaction in hypoxic renal interstitial fibrosis. | 0 |
| 36790221 | 2023 | Germline variation in RASAL2 may predict survival in patients with RAS-activated colorectal cancer. | 2 |
| 36790221 | 2023 | Germline variation in RASAL2 may predict survival in patients with RAS-activated colorectal cancer. | 2 |
| 34826200 | 2022 | Inhibition of Ras protein activator like 2 produces antitumor effects in gastric cancer via the suppression of YAP1 activation. | 0 |
| 35844783 | 2022 | RASAL2 mediated the enhancement of YAP1/TIAM1 signaling promotes malignant phenotypes of pancreatic ductal adenocarcinoma. | 0 |
| 34826200 | 2022 | Inhibition of Ras protein activator like 2 produces antitumor effects in gastric cancer via the suppression of YAP1 activation. | 0 |
| 35844783 | 2022 | RASAL2 mediated the enhancement of YAP1/TIAM1 signaling promotes malignant phenotypes of pancreatic ductal adenocarcinoma. | 0 |
| 33300072 | 2021 | miR‑654‑3p suppresses cell viability and promotes apoptosis by targeting RASAL2 in non‑small‑cell lung cancer. | 12 |
| 33563064 | 2021 | PRKAA/AMPKα phosphorylation switches the role of RASAL2 from a suppressor to an activator of autophagy. | 4 |
| 34193694 | 2021 | Low Expression of Rasal2 Promotes Non-small Cell Lung Cancer Metastasis through Ras/ERK Pathway. | 3 |
| 33300072 | 2021 | miR‑654‑3p suppresses cell viability and promotes apoptosis by targeting RASAL2 in non‑small‑cell lung cancer. | 12 |
| 33563064 | 2021 | PRKAA/AMPKα phosphorylation switches the role of RASAL2 from a suppressor to an activator of autophagy. | 4 |
Citation
Dessen P
RASAL2 (RAS protein activator like 2)
Atlas Genet Cytogenet Oncol Haematol. 2013-12-01
Online version: http://atlasgeneticsoncology.org/gene/53641/rasal2-(ras-protein-activator-like-2)
