Identity
HGNC
LOCATION
4q24
LOCUSID
ALIAS
ERIS,Miner1,NAF-1,WFS2,ZCD2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 493856
MIM: 611507
HGNC: 24212
Ensembl: ENSG00000145354
Variants:
dbSNP: 493856
ClinVar: 493856
TCGA: ENSG00000145354
COSMIC: CISD2
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38678819 | 2024 | A preliminary study unveils CISD2 as a ferroptosis-related therapeutic target for recurrent spontaneous abortion through immunological analysis and two-sample mendelian randomization. | 0 |
| 38814213 | 2024 | Overexpression of CISD2 alleviates septic acute kidney injury via activating Sonic Hedgehog signaling pathway. | 0 |
| 38678819 | 2024 | A preliminary study unveils CISD2 as a ferroptosis-related therapeutic target for recurrent spontaneous abortion through immunological analysis and two-sample mendelian randomization. | 0 |
| 38814213 | 2024 | Overexpression of CISD2 alleviates septic acute kidney injury via activating Sonic Hedgehog signaling pathway. | 0 |
| 37249759 | 2023 | CISD2 promotes lung squamous carcinoma cell migration and invasion via the TGF-β1-induced Smad2/3 signaling pathway. | 2 |
| 37249759 | 2023 | CISD2 promotes lung squamous carcinoma cell migration and invasion via the TGF-β1-induced Smad2/3 signaling pathway. | 2 |
| 35819709 | 2022 | CDGSH iron sulfur domain 2 mitigates apoptosis, oxidative stress and inflammatory response caused by oxygen-glucose deprivation/reoxygenation in HT22 hippocampal neurons by Akt-Nrf2-activated pathway. | 1 |
| 35819709 | 2022 | CDGSH iron sulfur domain 2 mitigates apoptosis, oxidative stress and inflammatory response caused by oxygen-glucose deprivation/reoxygenation in HT22 hippocampal neurons by Akt-Nrf2-activated pathway. | 1 |
| 33422617 | 2021 | CISD2 maintains cellular homeostasis. | 28 |
| 33477809 | 2021 | The NFκB Antagonist CDGSH Iron-Sulfur Domain 2 Is a Promising Target for the Treatment of Neurodegenerative Diseases. | 7 |
| 33752060 | 2021 | CISD2 plays a role in age-related diseases and cancer. | 6 |
| 34547371 | 2021 | Disrupting CISD2 function in cancer cells primarily impacts mitochondrial labile iron levels and triggers TXNIP expression. | 18 |
| 34740104 | 2021 | Cisd2 plays an essential role in corneal epithelial regeneration. | 9 |
| 33422617 | 2021 | CISD2 maintains cellular homeostasis. | 28 |
| 33477809 | 2021 | The NFκB Antagonist CDGSH Iron-Sulfur Domain 2 Is a Promising Target for the Treatment of Neurodegenerative Diseases. | 7 |
Citation
Dessen P
CISD2 (CDGSH iron sulfur domain 2)
Atlas Genet Cytogenet Oncol Haematol. 2013-12-01
Online version: http://atlasgeneticsoncology.org/gene/53644/cisd2-(cdgsh-iron-sulfur-domain-2)
