MORC4 (MORC family CW-type zinc finger 4)

2014-01-01  

Identity

HGNC
LOCATION
Xq22.3
LOCUSID
ALIAS
ZCW4,ZCWCC2,dJ75H8.2
FUSION GENES

Other Information

Locus ID:

NCBI: 79710
MIM: 300970
HGNC: 23485
Ensembl: ENSG00000133131

Variants:

dbSNP: 79710
ClinVar: 79710
TCGA: ENSG00000133131
COSMIC: MORC4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000133131ENST00000255495Q8TE76
ENSG00000133131ENST00000355610Q8TE76
ENSG00000133131ENST00000604604S4R3U3

Expression (GTEx)

0
5
10
15
20
25

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
369321962023MORC4 plays a tumor-promoting role in colorectal cancer via regulating PCGF1/CDKN1A axis in vitro and in vivo.1
369321962023MORC4 plays a tumor-promoting role in colorectal cancer via regulating PCGF1/CDKN1A axis in vitro and in vivo.1
303209202019MORC4 is a novel breast cancer oncogene regulated by miR-193b-3p.17
303209202019MORC4 is a novel breast cancer oncogene regulated by miR-193b-3p.17
289138782018Do pancreatic cancer and chronic pancreatitis share the same genetic risk factors? A PANcreatic Disease ReseArch (PANDoRA) consortium investigation.8
289138782018Do pancreatic cancer and chronic pancreatitis share the same genetic risk factors? A PANcreatic Disease ReseArch (PANDoRA) consortium investigation.8
268206202016Common Variants in CLDN2 and MORC4 Genes Confer Disease Susceptibility in Patients with Chronic Pancreatitis.14
268271812016Single Nucleotide Polymorphisms in MORC4, CD14, and TLR4 Are Related to Outcome of Allogeneic Stem Cell Transplantation.4
268206202016Common Variants in CLDN2 and MORC4 Genes Confer Disease Susceptibility in Patients with Chronic Pancreatitis.14
268271812016Single Nucleotide Polymorphisms in MORC4, CD14, and TLR4 Are Related to Outcome of Allogeneic Stem Cell Transplantation.4
252531272015Polymorphisms at PRSS1-PRSS2 and CLDN2-MORC4 loci associate with alcoholic and non-alcoholic chronic pancreatitis in a European replication study.39
252531272015Polymorphisms at PRSS1-PRSS2 and CLDN2-MORC4 loci associate with alcoholic and non-alcoholic chronic pancreatitis in a European replication study.39
239465982013Analysis of single nucleotide polymorphisms in the region of CLDN2-MORC4 in relation to inflammatory bowel disease.6
239465982013Analysis of single nucleotide polymorphisms in the region of CLDN2-MORC4 in relation to inflammatory bowel disease.6

Citation

Dessen P

MORC4 (MORC family CW-type zinc finger 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-01-01

Online version: http://atlasgeneticsoncology.org/gene/53654/morc4-(morc-family-cw-type-zinc-finger-4)