Identity
HGNC
LOCATION
20q11.22
LOCUSID
ALIAS
EIF2,EIF2B,EIF2beta,PPP1R67,eIF-2-beta
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8894
MIM: 603908
HGNC: 3266
Ensembl: ENSG00000125977
Variants:
dbSNP: 8894
ClinVar: 8894
TCGA: ENSG00000125977
COSMIC: EIF2S2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000125977 | ENST00000374980 | P20042 |
| ENSG00000125977 | ENST00000374980 | Q6IBR8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38159565 | 2024 | Recruitment of trimeric eIF2 by phosphatase non-catalytic subunit PPP1R15B. | 1 |
| 38159565 | 2024 | Recruitment of trimeric eIF2 by phosphatase non-catalytic subunit PPP1R15B. | 1 |
| 32059763 | 2020 | RBP EIF2S2 Promotes Tumorigenesis and Progression by Regulating MYC-Mediated Inhibition via FHIT-Related Enhancers. | 24 |
| 32059763 | 2020 | RBP EIF2S2 Promotes Tumorigenesis and Progression by Regulating MYC-Mediated Inhibition via FHIT-Related Enhancers. | 24 |
| 29624814 | 2018 | eIF2β, a subunit of translation-initiation factor EIF2, is a potential therapeutic target for non-small cell lung cancer. | 12 |
| 29624814 | 2018 | eIF2β, a subunit of translation-initiation factor EIF2, is a potential therapeutic target for non-small cell lung cancer. | 12 |
| 26609049 | 2016 | Association of eukaryotic translation initiation factor eIF2B with fully solubilized CXCR4. | 8 |
| 26609049 | 2016 | Association of eukaryotic translation initiation factor eIF2B with fully solubilized CXCR4. | 8 |
| 22813744 | 2012 | The C-terminal domain of eukaryotic initiation factor 5 promotes start codon recognition by its dynamic interplay with eIF1 and eIF2β. | 50 |
| 22813744 | 2012 | The C-terminal domain of eukaryotic initiation factor 5 promotes start codon recognition by its dynamic interplay with eIF1 and eIF2β. | 50 |
| 18639529 | 2008 | Intersubunit and interprotein interactions of alpha- and beta-subunits of human eIF2: Effect of phosphorylation. | 4 |
| 18639529 | 2008 | Intersubunit and interprotein interactions of alpha- and beta-subunits of human eIF2: Effect of phosphorylation. | 4 |
Citation
Dessen P
EIF2S2 (eukaryotic translation initiation factor 2 subunit beta)
Atlas Genet Cytogenet Oncol Haematol. 2014-01-01
Online version: http://atlasgeneticsoncology.org/gene/53658/eif2s2-(eukaryotic-translation-initiation-factor-2-subunit-beta)
