Identity
HGNC
LOCATION
19p13.2
LOCUSID
ALIAS
CD209L,CD299,DC-SIGN2,DC-SIGNR,DCSIGNR,HP10347,L-SIGN,LSIGN
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10332
MIM: 605872
HGNC: 13523
Ensembl: ENSG00000104938
Variants:
dbSNP: 10332
ClinVar: 10332
TCGA: ENSG00000104938
COSMIC: CLEC4M
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Phagosome | KEGG | ko04145 |
| Phagosome | KEGG | hsa04145 |
| Measles | KEGG | ko05162 |
| Measles | KEGG | hsa05162 |
| Tuberculosis | KEGG | ko05152 |
| Tuberculosis | KEGG | hsa05152 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33880537 | 2021 | ACE2, TMPRSS2, and L-SIGN Expression in Placentae From HIV-Positive Pregnancies Exposed to Antiretroviral Therapy-Implications for SARS-CoV-2 Placental Infection. | 1 |
| 33880537 | 2021 | ACE2, TMPRSS2, and L-SIGN Expression in Placentae From HIV-Positive Pregnancies Exposed to Antiretroviral Therapy-Implications for SARS-CoV-2 Placental Infection. | 1 |
| 32705212 | 2020 | CLEC4M overexpression inhibits progression and is associated with a favorable prognosis in hepatocellular carcinoma. | 4 |
| 32705212 | 2020 | CLEC4M overexpression inhibits progression and is associated with a favorable prognosis in hepatocellular carcinoma. | 4 |
| 30740857 | 2019 | The endothelial lectin clearance receptor CLEC4M binds and internalizes factor VIII in a VWF-dependent and independent manner. | 22 |
| 30740857 | 2019 | The endothelial lectin clearance receptor CLEC4M binds and internalizes factor VIII in a VWF-dependent and independent manner. | 22 |
| 29389944 | 2018 | Genetic variation in the C-type lectin receptor CLEC4M in type 1 von Willebrand Disease patients. | 3 |
| 29389944 | 2018 | Genetic variation in the C-type lectin receptor CLEC4M in type 1 von Willebrand Disease patients. | 3 |
| 27859859 | 2017 | Oligomerization domains in the glycan-binding receptors DC-SIGN and DC-SIGNR: Sequence variation and stability differences. | 6 |
| 28403883 | 2017 | DC - SIGNR by influencing the lncRNA HNRNPKP2 upregulates the expression of CXCR4 in gastric cancer liver metastasis. | 23 |
| 27859859 | 2017 | Oligomerization domains in the glycan-binding receptors DC-SIGN and DC-SIGNR: Sequence variation and stability differences. | 6 |
| 28403883 | 2017 | DC - SIGNR by influencing the lncRNA HNRNPKP2 upregulates the expression of CXCR4 in gastric cancer liver metastasis. | 23 |
| 27309478 | 2016 | Association of DC-SIGN and DC-SIGNR Repeat Regions with Susceptibility to Pulmonary Tuberculosis in Zahedan, Southeastern Iran. | 0 |
| 27334579 | 2016 | DC-SIGN and L-SIGN Are Attachment Factors That Promote Infection of Target Cells by Human Metapneumovirus in the Presence or Absence of Cellular Glycosaminoglycans. | 6 |
| 27309478 | 2016 | Association of DC-SIGN and DC-SIGNR Repeat Regions with Susceptibility to Pulmonary Tuberculosis in Zahedan, Southeastern Iran. | 0 |
Citation
Dessen P
CLEC4M (C-type lectin domain family 4 member M)
Atlas Genet Cytogenet Oncol Haematol. 2014-01-01
Online version: http://atlasgeneticsoncology.org/gene/53673/clec4m-(c-type-lectin-domain-family-4-member-m)
