TECTA (tectorin alpha)

2014-01-01 Affiliation

Identity

HGNC

TECTA

LOCATION

11q23.3

LOCUSID

7007

ALIAS

DFNA12,DFNA8,DFNB21

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 7007
MIM: 602574
HGNC: 11720
Ensembl: ENSG00000109927

Variants:

dbSNP: 7007
ClinVar: 7007
TCGA: ENSG00000109927
COSMIC: TECTA

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000109927	ENST00000264037	O75443
ENSG00000109927	ENST00000392793	O75443
ENSG00000109927	ENST00000642222	A0A2R8YDL0
ENSG00000109927	ENST00000645008	A0A2R8YGQ5

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Metabolism of proteins	REACTOME	R-HSA-392499
Post-translational protein modification	REACTOME	R-HSA-597592
Post-translational modification: synthesis of GPI-anchored proteins	REACTOME	R-HSA-163125

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
35870179	2022	Characterization of a possible founder synonymous variant in TECTA in multiple individuals with autosomal recessive hearing loss.	0
35870179	2022	Characterization of a possible founder synonymous variant in TECTA in multiple individuals with autosomal recessive hearing loss.	0
33976695	2021	Next-Generation Sequencing Identifies Pathogenic Variants in HGF, POU3F4, TECTA, and MYO7A in Consanguineous Pakistani Deaf Families.	2
33976695	2021	Next-Generation Sequencing Identifies Pathogenic Variants in HGF, POU3F4, TECTA, and MYO7A in Consanguineous Pakistani Deaf Families.	2
32382995	2020	A comparative analysis of genetic hearing loss phenotypes in European/American and Japanese populations.	12
32382995	2020	A comparative analysis of genetic hearing loss phenotypes in European/American and Japanese populations.	12
30703234	2019	[Diagnosis and reproductive guidance for a couple carrying a novel c.1893C>T mutation of the TECTA gene].	0
30703234	2019	[Diagnosis and reproductive guidance for a couple carrying a novel c.1893C>T mutation of the TECTA gene].	0
28012541	2017	A novel TECTA mutation causes ARNSHL.	8
28946916	2017	Prevalence of TECTA mutation in patients with mid-frequency sensorineural hearing loss.	11
28012541	2017	A novel TECTA mutation causes ARNSHL.	8
28946916	2017	Prevalence of TECTA mutation in patients with mid-frequency sensorineural hearing loss.	11
27142990	2016	Research progress in pathogenic genes of hereditary non-syndromic mid-frequency deafness.	6
27368438	2016	A novel biallelic splice site mutation of TECTA causes moderate to severe hearing impairment in an Algerian family.	7
27142990	2016	Research progress in pathogenic genes of hereditary non-syndromic mid-frequency deafness.	6

Citation

Dessen P

TECTA (tectorin alpha)

Atlas Genet Cytogenet Oncol Haematol. 2014-01-01

Online version: http://atlasgeneticsoncology.org/gene/53676/tecta-(tectorin-alpha)