LY6D (lymphocyte antigen 6 family member D)

2014-01-01  

Identity

HGNC
LOCATION
8q24.3
LOCUSID
ALIAS
E48,Ly-6D
FUSION GENES

Other Information

Locus ID:

NCBI: 8581
MIM: 606204
HGNC: 13348
Ensembl: ENSG00000167656

Variants:

dbSNP: 8581
ClinVar: 8581
TCGA: ENSG00000167656
COSMIC: LY6D

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167656ENST00000301263Q14210

Expression (GTEx)

0
500
1000
1500
2000
2500

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Post-translational modification: synthesis of GPI-anchored proteinsREACTOMER-HSA-163125

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
380675062023Silencing LY6D Expression Inhibits Colon Cancer in Xenograft Mice and Regulates Colon Cancer Stem Cells' Proliferation, Stemness, Invasion, and Apoptosis via the MAPK Pathway.0
380675062023Silencing LY6D Expression Inhibits Colon Cancer in Xenograft Mice and Regulates Colon Cancer Stem Cells' Proliferation, Stemness, Invasion, and Apoptosis via the MAPK Pathway.0
331686312021LY6D-induced macropinocytosis as a survival mechanism of senescent cells.4
341845662021Investigation of Candidate Genes and Pathways in Basal/TNBC Patients by Integrated Analysis.6
331686312021LY6D-induced macropinocytosis as a survival mechanism of senescent cells.4
341845662021Investigation of Candidate Genes and Pathways in Basal/TNBC Patients by Integrated Analysis.6
301376882018OLFM4, LY6D and S100A7 as potent markers for distant metastasis in estrogen receptor-positive breast carcinoma.29
305668732018Single-Cell Analysis Identifies LY6D as a Marker Linking Castration-Resistant Prostate Luminal Cells to Prostate Progenitors and Cancer.51
301376882018OLFM4, LY6D and S100A7 as potent markers for distant metastasis in estrogen receptor-positive breast carcinoma.29
305668732018Single-Cell Analysis Identifies LY6D as a Marker Linking Castration-Resistant Prostate Luminal Cells to Prostate Progenitors and Cancer.51
262237062016Up-regulation of lymphocyte antigen 6 complex expression in side-population cells derived from a human trophoblast cell line HTR-8/SVneo.1
262237062016Up-regulation of lymphocyte antigen 6 complex expression in side-population cells derived from a human trophoblast cell line HTR-8/SVneo.1
236723142013Expression of Ep-CAM, but not of E48, associates with nodal involvement in advanced squamous cell carcinomas of the larynx.3
236723142013Expression of Ep-CAM, but not of E48, associates with nodal involvement in advanced squamous cell carcinomas of the larynx.3
230754242012Expression of LY6D is induced at the surface of MCF10A cells by X-ray irradiation.5

Citation

Dessen P

LY6D (lymphocyte antigen 6 family member D)

Atlas Genet Cytogenet Oncol Haematol. 2014-01-01

Online version: http://atlasgeneticsoncology.org/gene/53679/ly6d-(lymphocyte-antigen-6-family-member-d)