Identity
HGNC
LOCATION
2q14.1
LOCUSID
ALIAS
FIL1,FIL1(EPSILON),FIL1E,IL-1F6,IL1(EPSILON),IL1F6
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 27179
MIM: 605509
HGNC: 15562
Ensembl: ENSG00000136694
Variants:
dbSNP: 27179
ClinVar: 27179
TCGA: ENSG00000136694
COSMIC: IL36A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000136694 | ENST00000259211 | Q9UHA7 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Cytokine Signaling in Immune system | REACTOME | R-HSA-1280215 |
| Signaling by Interleukins | REACTOME | R-HSA-449147 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38189700 | 2024 | Emerging Role of the IL-36/IL-36R Axis in Multiple Inflammatory Skin Diseases. | 2 |
| 38189700 | 2024 | Emerging Role of the IL-36/IL-36R Axis in Multiple Inflammatory Skin Diseases. | 2 |
| 38203575 | 2023 | Altered Gene Expression of IL-35 and IL-36α in the Skin of Patients with Atopic Dermatitis. | 1 |
| 38203575 | 2023 | Altered Gene Expression of IL-35 and IL-36α in the Skin of Patients with Atopic Dermatitis. | 1 |
| 34289144 | 2022 | IL-36α and IL-36γ expressions in the differential diagnosis of palmoplantar psoriasis and palmoplantar eczema: A retrospective histopathologic and immunohistochemical study. | 1 |
| 35049442 | 2022 | The Emerging Roles of IL-36, IL-37, and IL-38 in Diabetes Mellitus and its Complications. | 0 |
| 35667282 | 2022 | Interleukin-36α is elevated in diffuse systemic sclerosis and may potentiate fibrosis. | 0 |
| 35698471 | 2022 | IL-36 is Closely Related to Neutrophilic Inflammation in Chronic Obstructive Pulmonary Disease. | 0 |
| 35903102 | 2022 | IL-36 Cytokines: Their Roles in Asthma and Potential as a Therapeutic. | 5 |
| 34289144 | 2022 | IL-36α and IL-36γ expressions in the differential diagnosis of palmoplantar psoriasis and palmoplantar eczema: A retrospective histopathologic and immunohistochemical study. | 1 |
| 35049442 | 2022 | The Emerging Roles of IL-36, IL-37, and IL-38 in Diabetes Mellitus and its Complications. | 0 |
| 35667282 | 2022 | Interleukin-36α is elevated in diffuse systemic sclerosis and may potentiate fibrosis. | 0 |
| 35698471 | 2022 | IL-36 is Closely Related to Neutrophilic Inflammation in Chronic Obstructive Pulmonary Disease. | 0 |
| 35903102 | 2022 | IL-36 Cytokines: Their Roles in Asthma and Potential as a Therapeutic. | 5 |
| 33034926 | 2021 | Serum IL-36 cytokines levels in type 2 diabetes mellitus patients and their association with obesity, insulin resistance, and inflammation. | 8 |
Citation
Dessen P
IL36A (interleukin 36 alpha)
Atlas Genet Cytogenet Oncol Haematol. 2014-01-01
Online version: http://atlasgeneticsoncology.org/gene/53685/il36a-(interleukin-36-alpha)
