Identity
HGNC
LOCATION
22q11.1
LOCUSID
ALIAS
CANDF5,CD217,CDw217,IL-17RA,IL17R,IMD51,hIL-17R
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23765
MIM: 605461
HGNC: 5985
Ensembl: ENSG00000177663
Variants:
dbSNP: 23765
ClinVar: 23765
TCGA: ENSG00000177663
COSMIC: IL17RA
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000177663 | ENST00000319363 | Q96F46 |
| ENSG00000177663 | ENST00000612619 | Q96F46 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164713366 | Tumor necrosis factor alpha (TNF-alpha) inhibitors | Chemical | ClinicalAnnotation | associated | PD | 27670766 | |
| PA445451 | Psoriasis | Disease | ClinicalAnnotation | associated | PD | 27670766 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38491831 | 2024 | Decreased interleukin-17RA expression is associated with good prognosis in patients with colorectal cancer and inhibits tumor growth and vascularity in mice. | 0 |
| 38491831 | 2024 | Decreased interleukin-17RA expression is associated with good prognosis in patients with colorectal cancer and inhibits tumor growth and vascularity in mice. | 0 |
| 36790253 | 2023 | IL17A and IL17RA gene polymorphisms in Fanconi anemia. | 0 |
| 36979355 | 2023 | Immunogenic Cell Death Associated Molecular Patterns and the Dual Role of IL17RA in Interstitial Cystitis/Bladder Pain Syndrome. | 4 |
| 37239484 | 2023 | Association between IL-17F, IL-17RA Gene Polymorphisms and Response to Biological Drugs in Psoriasis and Beyond. | 1 |
| 37686343 | 2023 | Mechanistic Insights into the Roles of the IL-17/IL-17R Families in Pancreatic Cancer. | 2 |
| 37926850 | 2023 | Genetic association between interleukin-17 and susceptibility to rheumatoid arthritis. | 0 |
| 36790253 | 2023 | IL17A and IL17RA gene polymorphisms in Fanconi anemia. | 0 |
| 36979355 | 2023 | Immunogenic Cell Death Associated Molecular Patterns and the Dual Role of IL17RA in Interstitial Cystitis/Bladder Pain Syndrome. | 4 |
| 37239484 | 2023 | Association between IL-17F, IL-17RA Gene Polymorphisms and Response to Biological Drugs in Psoriasis and Beyond. | 1 |
| 37686343 | 2023 | Mechanistic Insights into the Roles of the IL-17/IL-17R Families in Pancreatic Cancer. | 2 |
| 37926850 | 2023 | Genetic association between interleukin-17 and susceptibility to rheumatoid arthritis. | 0 |
| 34384609 | 2022 | Polymorphisms at the IL17A and IL17RA Genes are Associated with Prognosis of Papillary Thyroid Carcinoma. | 3 |
| 35063672 | 2022 | Interleukin-7 and soluble Interleukin-7 receptor levels in type 1 diabetes - Impact of IL7RA polymorphisms, HLA risk genotypes and clinical features. | 3 |
| 35583128 | 2022 | Serum IL-17A concentration and a IL17RA single nucleotide polymorphism contribute to the risk of autoimmune type 1 diabetes. | 5 |
Citation
Dessen P
IL17RA (interleukin 17 receptor A)
Atlas Genet Cytogenet Oncol Haematol. 2013-08-01
Online version: http://atlasgeneticsoncology.org/gene/53729/il17ra-(interleukin-17-receptor-a)
