PEAK1 (pseudopodium enriched atypical kinase 1)

2013-08-01  

Identity

HGNC
LOCATION
15q24.3
LOCUSID
ALIAS
SGK269
FUSION GENES

Other Information

Locus ID:

NCBI: 79834
MIM: 614248
HGNC: 29431
Ensembl: ENSG00000173517

Variants:

dbSNP: 79834
ClinVar: 79834
TCGA: ENSG00000173517
COSMIC: PEAK1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173517ENST00000312493Q9H792
ENSG00000173517ENST00000558305H0YN99
ENSG00000173517ENST00000560626Q9H792
ENSG00000173517ENST00000564328H3BUZ5
ENSG00000173517ENST00000565820H3BUE6

Expression (GTEx)

0
5
10
15
20
25
30

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
345543182022PEAK1 promotes invasion and metastasis and confers drug resistance in breast cancer.3
356870212022PEAK1 Y635 phosphorylation regulates cell migration through association with Tensin3 and integrins.5
359965152022Clinical Significance of PEAK1 Expression and BRAF V600E Mutation in Papillary Thyroid Cancer.0
361487572022Exosome-delivered circSATB2 targets the miR-330-5p/PEAK1 axis to regulate proliferation, migration and invasion of lung cancer cells.4
345543182022PEAK1 promotes invasion and metastasis and confers drug resistance in breast cancer.3
356870212022PEAK1 Y635 phosphorylation regulates cell migration through association with Tensin3 and integrins.5
359965152022Clinical Significance of PEAK1 Expression and BRAF V600E Mutation in Papillary Thyroid Cancer.0
361487572022Exosome-delivered circSATB2 targets the miR-330-5p/PEAK1 axis to regulate proliferation, migration and invasion of lung cancer cells.4
337423352021LncRNA NORAD, sponging miR-363-3p, promotes invasion and EMT by upregulating PEAK1 and activating the ERK signaling pathway in NSCLC cells.11
342733982021BioID-Screening Identifies PEAK1 and SHP2 as Components of the ALK Proximitome in Neuroblastoma Cells.7
343659032021Pseudopodium enriched atypical kinase 1(PEAK1) promotes invasion and of melanoma cells by activating JAK/STAT3 signals.3
337423352021LncRNA NORAD, sponging miR-363-3p, promotes invasion and EMT by upregulating PEAK1 and activating the ERK signaling pathway in NSCLC cells.11
342733982021BioID-Screening Identifies PEAK1 and SHP2 as Components of the ALK Proximitome in Neuroblastoma Cells.7
343659032021Pseudopodium enriched atypical kinase 1(PEAK1) promotes invasion and of melanoma cells by activating JAK/STAT3 signals.3
326810752020AXL confers cell migration and invasion by hijacking a PEAK1-regulated focal adhesion protein network.28

Citation

Dessen P

PEAK1 (pseudopodium enriched atypical kinase 1)

Atlas Genet Cytogenet Oncol Haematol. 2013-08-01

Online version: http://atlasgeneticsoncology.org/gene/53735/peak1-(pseudopodium-enriched-atypical-kinase-1)