PGRMC2 (progesterone receptor membrane component 2)

2013-08-01  

Identity

HGNC
LOCATION
4q28.2
LOCUSID
ALIAS
DG6,PMBP
FUSION GENES

Other Information

Locus ID:

NCBI: 10424
MIM: 607735
HGNC: 16089
Ensembl: ENSG00000164040

Variants:

dbSNP: 10424
ClinVar: 10424
TCGA: ENSG00000164040
COSMIC: PGRMC2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164040ENST00000296425O15173
ENSG00000164040ENST00000394276D3DNX8
ENSG00000164040ENST00000503588U3KQM0
ENSG00000164040ENST00000503872D3DNX8
ENSG00000164040ENST00000509070U3KQ70
ENSG00000164040ENST00000512483D3DNX8
ENSG00000164040ENST00000520121O15173
ENSG00000164040ENST00000613358O15173

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
384523492024Deciphering the role of PGRMC2 in the human endometrium during the menstrual cycle and in vitro decidualization using an in vitro approach.0
384523492024Deciphering the role of PGRMC2 in the human endometrium during the menstrual cycle and in vitro decidualization using an in vitro approach.0
376652392023Progesterone receptor membrane component 2 is critical for human placental extravillous trophoblast invasion.1
376652392023Progesterone receptor membrane component 2 is critical for human placental extravillous trophoblast invasion.1
355267812022The role of progesterone receptor membrane component (PGRMC) in the endometrium.2
355267812022The role of progesterone receptor membrane component (PGRMC) in the endometrium.2
317487412019PGRMC2 is an intracellular haem chaperone critical for adipocyte function.58
318109112019Differential miRNA Expression in Basaloid Squamous Cell Carcinoma of the Oesophagus: miR-3687 Targets PGRMC2.2
317487412019PGRMC2 is an intracellular haem chaperone critical for adipocyte function.58
318109112019Differential miRNA Expression in Basaloid Squamous Cell Carcinoma of the Oesophagus: miR-3687 Targets PGRMC2.2
252666502016Changes in myometrial expression of progesterone receptor membrane components 1 and 2 are associated with human parturition at term.5
252666502016Changes in myometrial expression of progesterone receptor membrane components 1 and 2 are associated with human parturition at term.5
237934722014Expression patterns of progesterone receptor membrane components 1 and 2 in endometria from women with and without endometriosis.17
237934722014Expression patterns of progesterone receptor membrane components 1 and 2 in endometria from women with and without endometriosis.17
232766312013PGRMC2, a yet uncharacterized protein with potential as tumor suppressor, migration inhibitor, and regulator of cytochrome P450 enzyme activity.26

Citation

Dessen P

PGRMC2 (progesterone receptor membrane component 2)

Atlas Genet Cytogenet Oncol Haematol. 2013-08-01

Online version: http://atlasgeneticsoncology.org/gene/53736/pgrmc2-(progesterone-receptor-membrane-component-2)