Identity
HGNC
LOCATION
11p11.2
LOCUSID
ALIAS
DUSP23,MOSP,PLIP,PNAS-129
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 114971
MIM: 609538
HGNC: 26965
Ensembl: ENSG00000110536
Variants:
dbSNP: 114971
ClinVar: 114971
TCGA: ENSG00000110536
COSMIC: PTPMT1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000110536 | ENST00000326656 | Q8WUK0 |
| ENSG00000110536 | ENST00000326674 | Q8WUK0 |
| ENSG00000110536 | ENST00000426530 | Q8WUK0 |
| ENSG00000110536 | ENST00000534775 | E9PQM0 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33503428 | 2021 | Genome-wide CRISPR-Cas9 knockout library screening identified PTPMT1 in cardiolipin synthesis is crucial to survival in hypoxia in liver cancer. | 24 |
| 33992102 | 2021 | Splicing factor SRSF1 promotes breast cancer progression via oncogenic splice switching of PTPMT1. | 33 |
| 33503428 | 2021 | Genome-wide CRISPR-Cas9 knockout library screening identified PTPMT1 in cardiolipin synthesis is crucial to survival in hypoxia in liver cancer. | 24 |
| 33992102 | 2021 | Splicing factor SRSF1 promotes breast cancer progression via oncogenic splice switching of PTPMT1. | 33 |
| 30429088 | 2018 | SRSF1 modulates PTPMT1 alternative splicing to regulate lung cancer cell radioresistance. | 48 |
| 30429088 | 2018 | SRSF1 modulates PTPMT1 alternative splicing to regulate lung cancer cell radioresistance. | 48 |
| 26898802 | 2016 | Ptpmt1 induced by HIF-2α regulates the proliferation and glucose metabolism in erythroleukemia cells. | 6 |
| 26898802 | 2016 | Ptpmt1 induced by HIF-2α regulates the proliferation and glucose metabolism in erythroleukemia cells. | 6 |
| 24709986 | 2014 | The pseudophosphatase MK-STYX physically and genetically interacts with the mitochondrial phosphatase PTPMT1. | 12 |
| 24709986 | 2014 | The pseudophosphatase MK-STYX physically and genetically interacts with the mitochondrial phosphatase PTPMT1. | 12 |
| 23326511 | 2013 | Downregulation of the mitochondrial phosphatase PTPMT1 is sufficient to promote cancer cell death. | 15 |
| 23326511 | 2013 | Downregulation of the mitochondrial phosphatase PTPMT1 is sufficient to promote cancer cell death. | 15 |
Citation
Dessen P
PTPMT1 (protein tyrosine phosphatase mitochondrial 1)
Atlas Genet Cytogenet Oncol Haematol. 2013-08-01
Online version: http://atlasgeneticsoncology.org/gene/53737/ptpmt1-(protein-tyrosine-phosphatase-mitochondrial-1)
