PBLD (phenazine biosynthesis like protein domain containing)

2013-12-01  

Identity

HGNC
LOCATION
10q21.3
LOCUSID
ALIAS
HEL-S-306,MAWBP,MAWDBP
FUSION GENES

Other Information

Locus ID:

NCBI: 64081
MIM: 612189
HGNC: 23301
Ensembl: ENSG00000108187

Variants:

dbSNP: 64081
ClinVar: 64081
TCGA: ENSG00000108187
COSMIC: PBLD

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000108187ENST00000309049P30039
ENSG00000108187ENST00000309049A0A024QZK5
ENSG00000108187ENST00000336578A0A0C4DFS0
ENSG00000108187ENST00000358769P30039
ENSG00000108187ENST00000358769A0A024QZK5
ENSG00000108187ENST00000468798V9GY00
ENSG00000108187ENST00000495025P30039

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
351403332022PBLD inhibits angiogenesis via impeding VEGF/VEGFR2-mediated microenvironmental cross-talk between HCC cells and endothelial cells.14
351403332022PBLD inhibits angiogenesis via impeding VEGF/VEGFR2-mediated microenvironmental cross-talk between HCC cells and endothelial cells.14
331213242020Long noncoding RNA MEG3 suppresses cell proliferation, migration and invasion, induces apoptosis and paclitaxel-resistance via miR-4513/PBLD axis in breast cancer cells.15
331213242020Long noncoding RNA MEG3 suppresses cell proliferation, migration and invasion, induces apoptosis and paclitaxel-resistance via miR-4513/PBLD axis in breast cancer cells.15
314062522019circKDM4C suppresses tumor progression and attenuates doxorubicin resistance by regulating miR-548p/PBLD axis in breast cancer.75
314062522019circKDM4C suppresses tumor progression and attenuates doxorubicin resistance by regulating miR-548p/PBLD axis in breast cancer.75
265947982016Decreased expression of PBLD correlates with poor prognosis and functions as a tumor suppressor in human hepatocellular carcinoma.12
265947982016Decreased expression of PBLD correlates with poor prognosis and functions as a tumor suppressor in human hepatocellular carcinoma.12
263732882015Mitogen-activated protein kinase activator with WD40 repeats (MAWD) and MAWD-binding protein induce cell differentiation in gastric cancer.5
263732882015Mitogen-activated protein kinase activator with WD40 repeats (MAWD) and MAWD-binding protein induce cell differentiation in gastric cancer.5
236874152013MAWBP and MAWD inhibit proliferation and invasion in gastric cancer.8
236874152013MAWBP and MAWD inhibit proliferation and invasion in gastric cancer.8
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.83
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.83

Citation

Dessen P

PBLD (phenazine biosynthesis like protein domain containing)

Atlas Genet Cytogenet Oncol Haematol. 2013-12-01

Online version: http://atlasgeneticsoncology.org/gene/53749/pbld-(phenazine-biosynthesis-like-protein-domain-containing)