RFFL (ring finger and FYVE like domain containing E3 ubiquitin protein ligase)
2013-12-01 AffiliationIdentity
HGNC
LOCATION
17q12
LOCUSID
ALIAS
CARP-2,CARP2,FRING,RIFIFYLIN,RNF189,RNF34L
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 117584
MIM: 609735
HGNC: 24821
Ensembl: ENSG00000092871
Variants:
dbSNP: 117584
ClinVar: 117584
TCGA: ENSG00000092871
COSMIC: RFFL
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38367666 | 2024 | E3 ubiquitin ligase rififylin has yin and yang effects on rabbit cardiac transient outward potassium currents (I(to)) and corresponding channel proteins. | 0 |
| 38367666 | 2024 | E3 ubiquitin ligase rififylin has yin and yang effects on rabbit cardiac transient outward potassium currents (I(to)) and corresponding channel proteins. | 0 |
| 30401747 | 2019 | Trafficking of the human ether-a-go-go-related gene (hERG) potassium channel is regulated by the ubiquitin ligase rififylin (RFFL). | 9 |
| 30659120 | 2019 | The integral function of the endocytic recycling compartment is regulated by RFFL-mediated ubiquitylation of Rab11 effectors. | 13 |
| 30401747 | 2019 | Trafficking of the human ether-a-go-go-related gene (hERG) potassium channel is regulated by the ubiquitin ligase rififylin (RFFL). | 9 |
| 30659120 | 2019 | The integral function of the endocytic recycling compartment is regulated by RFFL-mediated ubiquitylation of Rab11 effectors. | 13 |
| 28827789 | 2017 | Positional cloning of quantitative trait nucleotides for blood pressure and cardiac QT-interval by targeted CRISPR/Cas9 editing of a novel long non-coding RNA. | 14 |
| 28827789 | 2017 | Positional cloning of quantitative trait nucleotides for blood pressure and cardiac QT-interval by targeted CRISPR/Cas9 editing of a novel long non-coding RNA. | 14 |
| 24114843 | 2013 | Different Raf protein kinases mediate different signaling pathways to stimulate E3 ligase RFFL gene expression in cell migration regulation. | 9 |
| 24114843 | 2013 | Different Raf protein kinases mediate different signaling pathways to stimulate E3 ligase RFFL gene expression in cell migration regulation. | 9 |
| 21308745 | 2011 | Destabilization of CARP mRNAs by aloe-emodin contributes to caspase-8-mediated p53-independent apoptosis of human carcinoma cells. | 9 |
| 21308745 | 2011 | Destabilization of CARP mRNAs by aloe-emodin contributes to caspase-8-mediated p53-independent apoptosis of human carcinoma cells. | 9 |
| 20677014 | 2010 | An approach based on a genome-wide association study reveals candidate loci for narcolepsy. | 19 |
| 20677014 | 2010 | An approach based on a genome-wide association study reveals candidate loci for narcolepsy. | 19 |
| 19305408 | 2009 | Common variants at ten loci influence QT interval duration in the QTGEN Study. | 208 |
Citation
Dessen P
RFFL (ring finger and FYVE like domain containing E3 ubiquitin protein ligase)
Atlas Genet Cytogenet Oncol Haematol. 2013-12-01
Online version: http://atlasgeneticsoncology.org/gene/53751/rffl-(ring-finger-and-fyve-like-domain-containing-e3-ubiquitin-protein-ligase)
