TPST1 (tyrosylprotein sulfotransferase 1)

2013-12-01  

Identity

HGNC
TPST1
LOCATION
7q11.21
LOCUSID
8460
ALIAS
TANGO13A
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8460
MIM: 603125
HGNC: 12020
Ensembl: ENSG00000169902

Variants:

dbSNP: 8460
ClinVar: 8460
TCGA: ENSG00000169902
COSMIC: TPST1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169902ENST00000304842O60507
ENSG00000169902ENST00000304842A0A024RDK9
ENSG00000169902ENST00000442120C9K0F3
ENSG00000169902ENST00000451388C9J3I4
ENSG00000169902ENST00000649664O60507
ENSG00000169902ENST00000649664A0A024RDK9

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
250795142015Genetic variation in microRNA-binding site and prognosis of patients with colorectal cancer.8
262386322015Tyrosylprotein sulfotransferase 1 expression is negatively correlated with c‑Met and lymph node metastasis in human lung cancer.7
250795142015Genetic variation in microRNA-binding site and prognosis of patients with colorectal cancer.8
262386322015Tyrosylprotein sulfotransferase 1 expression is negatively correlated with c‑Met and lymph node metastasis in human lung cancer.7
234720692013Tyrosylprotein sulfotransferase-1 and tyrosine sulfation of chemokine receptor 4 are induced by Epstein-Barr virus encoded latent membrane protein 1 and associated with the metastatic potential of human nasopharyngeal carcinoma.26
234720692013Tyrosylprotein sulfotransferase-1 and tyrosine sulfation of chemokine receptor 4 are induced by Epstein-Barr virus encoded latent membrane protein 1 and associated with the metastatic potential of human nasopharyngeal carcinoma.26
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
193430462009Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.4
193430462009Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.4
186723802008Mass spectrometric kinetic analysis of human tyrosylprotein sulfotransferase-1 and -2.16
186723802008Mass spectrometric kinetic analysis of human tyrosylprotein sulfotransferase-1 and -2.16
168597062006Human TPST1 transmembrane domain triggers enzyme dimerisation and localisation to the Golgi compartment.13
168597062006Human TPST1 transmembrane domain triggers enzyme dimerisation and localisation to the Golgi compartment.13
162447082005Identification and characterization of tyrosylprotein sulfotransferase from human saliva.4

Citation

Dessen P

TPST1 (tyrosylprotein sulfotransferase 1)

Atlas Genet Cytogenet Oncol Haematol. 2013-12-01

Online version: http://atlasgeneticsoncology.org/gene/53753/tpst1-(tyrosylprotein-sulfotransferase-1)