TENT5C (terminal nucleotidyltransferase 5C)

2014-01-01  

Identity

HGNC
LOCATION
1p12
LOCUSID
ALIAS
FAM46C

Other Information

Locus ID:

NCBI: 54855
MIM: 613952
HGNC: 24712
Ensembl: ENSG00000183508

Variants:

dbSNP: 54855
ClinVar: 54855
TCGA: ENSG00000183508
COSMIC: TENT5C

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183508ENST00000369448Q5VWP2

References

Pubmed IDYearTitleCitations
371551542023FAM46C-mediated tumor heterogeneity predicts extramedullary metastasis and poorer survival in multiple myeloma.2
374676752023Hsa-miR-1269a up-regulation fosters the malignant progression of esophageal squamous cell carcinoma via targeting FAM46C.1
371551542023FAM46C-mediated tumor heterogeneity predicts extramedullary metastasis and poorer survival in multiple myeloma.2
374676752023Hsa-miR-1269a up-regulation fosters the malignant progression of esophageal squamous cell carcinoma via targeting FAM46C.1
340486382021Structural and functional characterization of multiple myeloma associated cytoplasmic poly(A) polymerase FAM46C.6
340486382021Structural and functional characterization of multiple myeloma associated cytoplasmic poly(A) polymerase FAM46C.6
315859032020FAM46C suppresses gastric cancer by inhibition of Wnt/beta-catenin.7
321417012020FAM46C controls antibody production by the polyadenylation of immunoglobulin mRNAs and inhibits cell migration in multiple myeloma.16
321768232020Biallelic loss of FAM46C triggers tumor growth with concomitant activation of Akt signaling in multiple myeloma cells.11
322239572020Down-regulation of miR-10b represses cell vitality in osteosarcoma and is inversely associated with prognosis via interacting with FAM46C: Running title: MiR-10b/FAM46C axis modulates OS progression.2
328078752020FAM46C/TENT5C functions as a tumor suppressor through inhibition of Plk4 activity.14
329630112020FAM46C and FNDC3A Are Multiple Myeloma Tumor Suppressors That Act in Concert to Impair Clearing of Protein Aggregates and Autophagy.13
329667802020The Interaction of the Tumor Suppressor FAM46C with p62 and FNDC3 Proteins Integrates Protein and Secretory Homeostasis.20
315859032020FAM46C suppresses gastric cancer by inhibition of Wnt/beta-catenin.7
321417012020FAM46C controls antibody production by the polyadenylation of immunoglobulin mRNAs and inhibits cell migration in multiple myeloma.16

Citation

Dessen P

TENT5C (terminal nucleotidyltransferase 5C)

Atlas Genet Cytogenet Oncol Haematol. 2014-01-01

Online version: http://atlasgeneticsoncology.org/gene/53755/tent5c-(terminal-nucleotidyltransferase-5c)