Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2312
MIM: 135940
HGNC: 3748
Ensembl: ENSG00000143631
Variants:
dbSNP: 2312
ClinVar: 2312
TCGA: ENSG00000143631
COSMIC: FLG
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000143631 | ENST00000368799 | P20930 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Developmental Biology | REACTOME | R-HSA-1266738 |
| Keratinization | REACTOME | R-HSA-6805567 |
| Formation of the cornified envelope | REACTOME | R-HSA-6809371 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36807394 | 2024 | Human filaggrin monomer does not seem to be a proteasome target. | 1 |
| 37650296 | 2024 | Temporal relationships between Staphylococcus aureus colonization, filaggrin expression, and pediatric atopic dermatitis. | 0 |
| 38302328 | 2024 | Influence of household pet ownership and filaggrin loss-of-function mutations on eczema prevalence in children: A birth cohort study. | 0 |
| 38414183 | 2024 | Association between filaggrin gene mutations and the clinical features of molluscum contagiosum: The Yamanashi Adjunct Study of the Japan Environment and Children's Study. | 0 |
| 38564302 | 2024 | Filaggrin loss-of-function variants are associated with atopic dermatitis phenotypes in a diverse, early-life prospective cohort. | 0 |
| 38677234 | 2024 | Immunolabeling for filaggrin and acidic keratins in the granular layer of mammalian epidermis indicates that an acidic-basic interaction is involved in cornification. | 0 |
| 38907248 | 2024 | Evaluation of OVOL1 and Filaggrin immunohistochemical expression and clinical relevance in psoriasis. | 0 |
| 38928170 | 2024 | Rare Filaggrin Variants Are Associated with Pustular Skin Diseases in Asians. | 0 |
| 36807394 | 2024 | Human filaggrin monomer does not seem to be a proteasome target. | 1 |
| 37650296 | 2024 | Temporal relationships between Staphylococcus aureus colonization, filaggrin expression, and pediatric atopic dermatitis. | 0 |
| 38302328 | 2024 | Influence of household pet ownership and filaggrin loss-of-function mutations on eczema prevalence in children: A birth cohort study. | 0 |
| 38414183 | 2024 | Association between filaggrin gene mutations and the clinical features of molluscum contagiosum: The Yamanashi Adjunct Study of the Japan Environment and Children's Study. | 0 |
| 38564302 | 2024 | Filaggrin loss-of-function variants are associated with atopic dermatitis phenotypes in a diverse, early-life prospective cohort. | 0 |
| 38677234 | 2024 | Immunolabeling for filaggrin and acidic keratins in the granular layer of mammalian epidermis indicates that an acidic-basic interaction is involved in cornification. | 0 |
| 38907248 | 2024 | Evaluation of OVOL1 and Filaggrin immunohistochemical expression and clinical relevance in psoriasis. | 0 |
Citation
Dessen P
FLG (filaggrin)
Atlas Genet Cytogenet Oncol Haematol. 2014-01-01
Online version: http://atlasgeneticsoncology.org/gene/53756/
