Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23409
MIM: 604482
HGNC: 14932
Ensembl: ENSG00000089163
Variants:
dbSNP: 23409
ClinVar: 23409
TCGA: ENSG00000089163
COSMIC: SIRT4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000089163 | ENST00000202967 | Q9Y6E7 |
| ENSG00000089163 | ENST00000536460 | F5H4X9 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38499327 | 2024 | SIRT4 as a novel interactor and candidate suppressor of C-RAF kinase in MAPK signaling. | 0 |
| 38548246 | 2024 | SIRT3 and SIRT4 double-genes remodeled the mitochondrial network to induce hepatocellular carcinoma cell line differentiation and suppress malignant phenotypes. | 1 |
| 38586875 | 2024 | SIRT4 promotes neuronal apoptosis in models of Alzheimer's disease via the STAT2-SIRT4-mTOR pathway. | 1 |
| 38499327 | 2024 | SIRT4 as a novel interactor and candidate suppressor of C-RAF kinase in MAPK signaling. | 0 |
| 38548246 | 2024 | SIRT3 and SIRT4 double-genes remodeled the mitochondrial network to induce hepatocellular carcinoma cell line differentiation and suppress malignant phenotypes. | 1 |
| 38586875 | 2024 | SIRT4 promotes neuronal apoptosis in models of Alzheimer's disease via the STAT2-SIRT4-mTOR pathway. | 1 |
| 36209169 | 2023 | Sirtuin 4 activates autophagy and inhibits tumorigenesis by upregulating the p53 signaling pathway. | 12 |
| 37067687 | 2023 | SIRT4 in ageing. | 3 |
| 37146713 | 2023 | Sirtuin4 impacts mitochondrial homeostasis in pancreatic cancer cells by reducing the stability of AlkB homolog 1 via deacetylation of the HRD1-SEL1L complex. | 3 |
| 37178383 | 2023 | The Regulation of GLT-1 Degradation Pathway by SIRT4. | 0 |
| 37541633 | 2023 | SIRT4 protects against intestinal fibrosis by facilitating GLS1 degradation. | 3 |
| 37858614 | 2023 | SIRT4 is a regulator of human skeletal muscle fatty acid metabolism influencing inner and outer mitochondrial membrane-mediated fusion. | 3 |
| 36209169 | 2023 | Sirtuin 4 activates autophagy and inhibits tumorigenesis by upregulating the p53 signaling pathway. | 12 |
| 37067687 | 2023 | SIRT4 in ageing. | 3 |
| 37146713 | 2023 | Sirtuin4 impacts mitochondrial homeostasis in pancreatic cancer cells by reducing the stability of AlkB homolog 1 via deacetylation of the HRD1-SEL1L complex. | 3 |
Citation
Dessen P
SIRT4 (sirtuin 4)
Atlas Genet Cytogenet Oncol Haematol. 2014-01-01
Online version: http://atlasgeneticsoncology.org/gene/53767/
