ATG9A (autophagy related 9A)

2014-02-01  

Identity

HGNC
LOCATION
2q35
LOCUSID
ALIAS
APG9L1,MGD3208,mATG9
FUSION GENES

Other Information

Locus ID:

NCBI: 79065
MIM: 612204
HGNC: 22408
Ensembl: ENSG00000198925

Variants:

dbSNP: 79065
ClinVar: 79065
TCGA: ENSG00000198925
COSMIC: ATG9A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198925ENST00000361242Q7Z3C6
ENSG00000198925ENST00000361242A0A024R438
ENSG00000198925ENST00000396761Q7Z3C6
ENSG00000198925ENST00000396761A0A024R438
ENSG00000198925ENST00000409033Q7Z3C6
ENSG00000198925ENST00000409422Q7Z3C6
ENSG00000198925ENST00000409618Q7Z3C6
ENSG00000198925ENST00000409618A0A024R438
ENSG00000198925ENST00000412355F2Z3I6
ENSG00000198925ENST00000428226C9JKV7
ENSG00000198925ENST00000429920H7C1G6
ENSG00000198925ENST00000431715C9JD65
ENSG00000198925ENST00000432520C9IYZ9
ENSG00000198925ENST00000434939C9JS65
ENSG00000198925ENST00000436856C9JXG2
ENSG00000198925ENST00000439812C9JX27
ENSG00000198925ENST00000443140C9JFV2
ENSG00000198925ENST00000456708F2Z3I6
ENSG00000198925ENST00000457841C9JDK4

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Autophagy - animalKEGGko04140
Autophagy - animalKEGGhsa04140
Cellular responses to stressREACTOMER-HSA-2262752
MacroautophagyREACTOMER-HSA-1632852
Mitophagy - animalKEGGko04137
Mitophagy - animalKEGGhsa04137
Autophagy - otherKEGGko04136
Autophagy - otherKEGGhsa04136

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
169403482006Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes.286
224565072012Dynamic and transient interactions of Atg9 with autophagosomes, but not membrane integration, are required for autophagy.162
248193842014Mutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagy.132
198934882010Coordinated regulation of autophagy by p38alpha MAPK through mAtg9 and p38IP.100
198934882010Coordinated regulation of autophagy by p38alpha MAPK through mAtg9 and p38IP.100
275109222016Autophagy initiation by ULK complex assembly on ER tubulovesicular regions marked by ATG9 vesicles.67
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
267111782016TBC1D14 regulates autophagy via the TRAPP complex and ATG9 traffic.61
210685422011Bif-1 regulates Atg9 trafficking by mediating the fission of Golgi membranes during autophagy.57
246034922014TBC1D5 and the AP2 complex regulate ATG9 trafficking and initiation of autophagy.54

Citation

Dessen P

ATG9A (autophagy related 9A)

Atlas Genet Cytogenet Oncol Haematol. 2014-02-01

Online version: http://atlasgeneticsoncology.org/gene/53804/atg9a-(autophagy-related-9a)