Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84681
MIM: 609997
HGNC: 18344
Ensembl: ENSG00000137133
Variants:
dbSNP: 84681
ClinVar: 84681
TCGA: ENSG00000137133
COSMIC: HINT2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000137133 | ENST00000259667 | Q9BX68 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37004779 | 2023 | Histidine triad nucleotide-binding protein 2: From basic science to clinical implications. | 1 |
| 37004779 | 2023 | Histidine triad nucleotide-binding protein 2: From basic science to clinical implications. | 1 |
| 34329705 | 2021 | Biochemical, crystallographic and biophysical characterization of histidine triad nucleotide-binding protein 2 with different ligands including a non-hydrolyzable analog of Ap4A. | 1 |
| 34329705 | 2021 | Biochemical, crystallographic and biophysical characterization of histidine triad nucleotide-binding protein 2 with different ligands including a non-hydrolyzable analog of Ap4A. | 1 |
| 31990367 | 2020 | Histidine triad nucleotide-binding proteins HINT1 and HINT2 share similar substrate specificities and little affinity for the signaling dinucleotide Ap4A. | 5 |
| 31990367 | 2020 | Histidine triad nucleotide-binding proteins HINT1 and HINT2 share similar substrate specificities and little affinity for the signaling dinucleotide Ap4A. | 5 |
| 31770197 | 2019 | Clinical significance of down-regulated HINT2 in hepatocellular carcinoma. | 1 |
| 31770197 | 2019 | Clinical significance of down-regulated HINT2 in hepatocellular carcinoma. | 1 |
| 29913563 | 2018 | The histidine triad nucleotide-binding protein 2 (HINT-2) positively regulates hepatocellular energy metabolism. | 6 |
| 29913563 | 2018 | The histidine triad nucleotide-binding protein 2 (HINT-2) positively regulates hepatocellular energy metabolism. | 6 |
| 28088787 | 2017 | HINT2 downregulation promotes colorectal carcinoma migration and metastasis. | 9 |
| 28947137 | 2017 | HINT2 triggers mitochondrial Ca(2+) influx by regulating the mitochondrial Ca(2+) uniporter (MCU) complex and enhances gemcitabine apoptotic effect in pancreatic cancer. | 26 |
| 28088787 | 2017 | HINT2 downregulation promotes colorectal carcinoma migration and metastasis. | 9 |
| 28947137 | 2017 | HINT2 triggers mitochondrial Ca(2+) influx by regulating the mitochondrial Ca(2+) uniporter (MCU) complex and enhances gemcitabine apoptotic effect in pancreatic cancer. | 26 |
| 23659632 | 2013 | Structural characterization of human histidine triad nucleotide-binding protein 2, a member of the histidine triad superfamily. | 8 |
Citation
Dessen P
HINT2 (histidine triad nucleotide binding protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-02-01
Online version: http://atlasgeneticsoncology.org/gene/53805/hint2-(histidine-triad-nucleotide-binding-protein-2)
