Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 340602
MIM: 301036
HGNC: 33738
Ensembl: ENSG00000187690
Variants:
dbSNP: 340602
ClinVar: 340602
TCGA: ENSG00000187690
COSMIC: EZHIP
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000187690 | ENST00000342995 | Q86X51 |
| ENSG00000187690 | ENST00000342995 | A0A515VFR0 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35511635 | 2022 | [The value of CXorf67 and H3K27me3 for diagnosing germ cell tumors in central nervous system]. | 0 |
| 35511635 | 2022 | [The value of CXorf67 and H3K27me3 for diagnosing germ cell tumors in central nervous system]. | 0 |
| 33130928 | 2021 | EZH2 inhibitory protein (EZHIP/Cxorf67) expression correlates strongly with H3K27me3 loss in posterior fossa ependymomas and is mutually exclusive with H3K27M mutations. | 13 |
| 33130928 | 2021 | EZH2 inhibitory protein (EZHIP/Cxorf67) expression correlates strongly with H3K27me3 loss in posterior fossa ependymomas and is mutually exclusive with H3K27M mutations. | 13 |
| 32193787 | 2020 | Histone H3 wild-type DIPG/DMG overexpressing EZHIP extend the spectrum diffuse midline gliomas with PRC2 inhibition beyond H3-K27M mutation. | 55 |
| 33153494 | 2020 | EZHIP is a specific diagnostic biomarker for posterior fossa ependymomas, group PFA and diffuse midline gliomas H3-WT with EZHIP overexpression. | 18 |
| 33186520 | 2020 | Elevated CXorf67 Expression in PFA Ependymomas Suppresses DNA Repair and Sensitizes to PARP Inhibitors. | 14 |
| 32193787 | 2020 | Histone H3 wild-type DIPG/DMG overexpressing EZHIP extend the spectrum diffuse midline gliomas with PRC2 inhibition beyond H3-K27M mutation. | 55 |
| 33153494 | 2020 | EZHIP is a specific diagnostic biomarker for posterior fossa ependymomas, group PFA and diffuse midline gliomas H3-WT with EZHIP overexpression. | 18 |
| 33186520 | 2020 | Elevated CXorf67 Expression in PFA Ependymomas Suppresses DNA Repair and Sensitizes to PARP Inhibitors. | 14 |
| 30923826 | 2019 | EZHIP/CXorf67 mimics K27M mutated oncohistones and functions as an intrinsic inhibitor of PRC2 function in aggressive posterior fossa ependymoma. | 68 |
| 31086175 | 2019 | PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism. | 83 |
| 31281901 | 2019 | CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism. | 56 |
| 31451685 | 2019 | EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells. | 47 |
| 30923826 | 2019 | EZHIP/CXorf67 mimics K27M mutated oncohistones and functions as an intrinsic inhibitor of PRC2 function in aggressive posterior fossa ependymoma. | 68 |
Citation
Dessen P
EZHIP (EZH inhibitory protein)
Atlas Genet Cytogenet Oncol Haematol. 2014-03-01
Online version: http://atlasgeneticsoncology.org/gene/53814
