Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 113510
MIM: 606769
HGNC: 18536
Ensembl: ENSG00000163312
Variants:
dbSNP: 113510
ClinVar: 113510
TCGA: ENSG00000163312
COSMIC: HELQ
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000163312 | ENST00000295488 | Q8TDG4 |
| ENSG00000163312 | ENST00000508591 | E3W982 |
| ENSG00000163312 | ENST00000510985 | E3W980 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38540391 | 2024 | A Human Homozygous HELQ Missense Variant Does Not Cause Premature Ovarian Insufficiency in a Mouse Model. | 0 |
| 38720471 | 2024 | HELQ deficiency impairs the induction of primordial germ cell-like cells. | 0 |
| 38540391 | 2024 | A Human Homozygous HELQ Missense Variant Does Not Cause Premature Ovarian Insufficiency in a Mouse Model. | 0 |
| 38720471 | 2024 | HELQ deficiency impairs the induction of primordial germ cell-like cells. | 0 |
| 36718939 | 2023 | Interaction of human HelQ with DNA polymerase delta halts DNA synthesis and stimulates DNA single-strand annealing. | 3 |
| 37777152 | 2023 | Mitotic DNA Synthesis in Untransformed Human Cells Preserves Common Fragile Site Stability via a FANCD2-Driven Mechanism That Requires HELQ. | 1 |
| 37897354 | 2023 | Human HELQ regulates DNA end resection at DNA double-strand breaks and stalled replication forks. | 0 |
| 36718939 | 2023 | Interaction of human HelQ with DNA polymerase delta halts DNA synthesis and stimulates DNA single-strand annealing. | 3 |
| 37777152 | 2023 | Mitotic DNA Synthesis in Untransformed Human Cells Preserves Common Fragile Site Stability via a FANCD2-Driven Mechanism That Requires HELQ. | 1 |
| 37897354 | 2023 | Human HELQ regulates DNA end resection at DNA double-strand breaks and stalled replication forks. | 0 |
| 33485349 | 2021 | HELQ and EGR3 expression correlate with IGHV mutation status and prognosis in chronic lymphocytic leukemia. | 3 |
| 34672775 | 2021 | Identification and Functional Investigation of Novel Heterozygous HELQ Mutations in Patients with Sertoli Cell-only Syndrome. | 3 |
| 33485349 | 2021 | HELQ and EGR3 expression correlate with IGHV mutation status and prognosis in chronic lymphocytic leukemia. | 3 |
| 34672775 | 2021 | Identification and Functional Investigation of Novel Heterozygous HELQ Mutations in Patients with Sertoli Cell-only Syndrome. | 3 |
| 29572031 | 2018 | Helicase POLQ-like (HELQ) as a novel indicator of platinum-based chemoresistance for epithelial ovarian cancer. | 8 |
Citation
Dessen P
HELQ (helicase, POLQ like)
Atlas Genet Cytogenet Oncol Haematol. 2014-03-01
Online version: http://atlasgeneticsoncology.org/gene/53819/helq-(helicase-polq-like)
