PARP10 (poly(ADP-ribose) polymerase family member 10)

2014-03-01  

Identity

HGNC
LOCATION
8q24.3
LOCUSID
ALIAS
ARTD10
FUSION GENES

Other Information

Locus ID:

NCBI: 84875
MIM: 609564
HGNC: 25895
Ensembl: ENSG00000178685

Variants:

dbSNP: 84875
ClinVar: 84875
TCGA: ENSG00000178685
COSMIC: PARP10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000178685ENST00000313028Q53GL7
ENSG00000178685ENST00000313059F8W8G7
ENSG00000178685ENST00000524918E9PK67
ENSG00000178685ENST00000525486E9PIK9
ENSG00000178685ENST00000525773E9PNI7
ENSG00000178685ENST00000525879E9PPV8
ENSG00000178685ENST00000527262E9PPE7
ENSG00000178685ENST00000528136E9PM86
ENSG00000178685ENST00000528625E9PJI2
ENSG00000178685ENST00000528914E9PSE7
ENSG00000178685ENST00000529311E9PQQ6
ENSG00000178685ENST00000529842E9PIA6
ENSG00000178685ENST00000530478E9PPU2
ENSG00000178685ENST00000531537E9PIA6
ENSG00000178685ENST00000531707E9PSG8
ENSG00000178685ENST00000532311E9PLE8

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of vitamins and cofactorsREACTOMER-HSA-196854
Metabolism of water-soluble vitamins and cofactorsREACTOMER-HSA-196849
Nicotinate metabolismREACTOMER-HSA-196807
Nicotinamide salvagingREACTOMER-HSA-197264

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
375062472023PARP10 is highly expressed and associated with inferior outcomes in acute myeloid leukemia.0
375062472023PARP10 is highly expressed and associated with inferior outcomes in acute myeloid leukemia.0
320604232020PLK1/NF-κB feedforward circuit antagonizes the mono-ADP-ribosyltransferase activity of PARP10 and facilitates HCC progression.16
323921942020[PARP10 Influences the Proliferation of Colorectal Carcinoma Cells, a Preliminary Study].7
330596802020The mono-ADP-ribosyltransferase ARTD10 regulates the voltage-gated K(+) channel Kv1.1 through protein kinase C delta.5
320604232020PLK1/NF-κB feedforward circuit antagonizes the mono-ADP-ribosyltransferase activity of PARP10 and facilitates HCC progression.16
323921942020[PARP10 Influences the Proliferation of Colorectal Carcinoma Cells, a Preliminary Study].7
330596802020The mono-ADP-ribosyltransferase ARTD10 regulates the voltage-gated K(+) channel Kv1.1 through protein kinase C delta.5
292935002018PARP10 (ARTD10) modulates mitochondrial function.30
295152342018PARP10 suppresses tumor metastasis through regulation of Aurora A activity.28
300322502018PARP10 promotes cellular proliferation and tumorigenesis by alleviating replication stress.43
292935002018PARP10 (ARTD10) modulates mitochondrial function.30
295152342018PARP10 suppresses tumor metastasis through regulation of Aurora A activity.28
300322502018PARP10 promotes cellular proliferation and tumorigenesis by alleviating replication stress.43
248787612015Function and regulation of the mono-ADP-ribosyltransferase ARTD10.18

Citation

Dessen P

PARP10 (poly(ADP-ribose) polymerase family member 10)

Atlas Genet Cytogenet Oncol Haematol. 2014-03-01

Online version: http://atlasgeneticsoncology.org/gene/53824/