PCOLCE (procollagen C-endopeptidase enhancer)

2014-03-01  

Identity

HGNC
LOCATION
7q22.1
LOCUSID
ALIAS
PCPE,PCPE-1,PCPE1
FUSION GENES

Other Information

Locus ID:

NCBI: 5118
MIM: 600270
HGNC: 8738
Ensembl: ENSG00000106333

Variants:

dbSNP: 5118
ClinVar: 5118
TCGA: ENSG00000106333
COSMIC: PCOLCE

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000106333ENST00000223061Q15113

Expression (GTEx)

0
100
200
300
400
500
600
700

Pathways

PathwaySourceExternal ID
Extracellular matrix organizationREACTOMER-HSA-1474244
Collagen formationREACTOMER-HSA-1474290
Collagen biosynthesis and modifying enzymesREACTOMER-HSA-1650814
Assembly of collagen fibrils and other multimeric structuresREACTOMER-HSA-2022090
Crosslinking of collagen fibrilsREACTOMER-HSA-2243919

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
368824572023High expression of PCOLCE gene indicate poor prognosis in patients and are associated with immune infiltration in glioma.0
368824572023High expression of PCOLCE gene indicate poor prognosis in patients and are associated with immune infiltration in glioma.0
351483342022Procollagen C-Proteinase Enhancer-1 (PCPE-1) deficiency in mice reduces liver fibrosis but not NASH progression.3
361735362022Procollagen C-proteinase enhancer-1 and renal failure in multiple myeloma.0
362526542022Expression of procollagen C-proteinase enhancer 1 in human trabecular meshwork tissues and cells.0
365960642022A pan-cancer analysis of the oncogenic role of procollagen C-endopeptidase enhancer (PCOLCE) in human.4
351483342022Procollagen C-Proteinase Enhancer-1 (PCPE-1) deficiency in mice reduces liver fibrosis but not NASH progression.3
361735362022Procollagen C-proteinase enhancer-1 and renal failure in multiple myeloma.0
362526542022Expression of procollagen C-proteinase enhancer 1 in human trabecular meshwork tissues and cells.0
365960642022A pan-cancer analysis of the oncogenic role of procollagen C-endopeptidase enhancer (PCOLCE) in human.4
303939142019Elevated serum levels of procollagen C-proteinase enhancer-1 in patients with chronic kidney disease is associated with a declining glomerular filtration rate.3
312857652019Up-regulation of PCOLCE by TWIST1 promotes metastasis in Osteosarcoma.40
303939142019Elevated serum levels of procollagen C-proteinase enhancer-1 in patients with chronic kidney disease is associated with a declining glomerular filtration rate.3
312857652019Up-regulation of PCOLCE by TWIST1 promotes metastasis in Osteosarcoma.40
296839802018Evaluation of serum procollagen C-proteinase enhancer 1 level as a fibrosis marker in patients with chronic hepatitis B.3

Citation

Dessen P

PCOLCE (procollagen C-endopeptidase enhancer)

Atlas Genet Cytogenet Oncol Haematol. 2014-03-01

Online version: http://atlasgeneticsoncology.org/gene/53825/