Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6614
MIM: 600751
HGNC: 11127
Ensembl: ENSG00000088827
Variants:
dbSNP: 6614
ClinVar: 6614
TCGA: ENSG00000088827
COSMIC: SIGLEC1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000088827 | ENST00000344754 | Q9BZZ2 |
| ENSG00000088827 | ENST00000419548 | H7C0M6 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38349399 | 2024 | A novel subpopulation of monocytes with a strong interferon signature indicated by SIGLEC-1 is present in patients with in recent-onset type 1 diabetes. | 0 |
| 38349399 | 2024 | A novel subpopulation of monocytes with a strong interferon signature indicated by SIGLEC-1 is present in patients with in recent-onset type 1 diabetes. | 0 |
| 34494938 | 2023 | The role of sialic acid-binding immunoglobulin-like-lectin-1 (siglec-1) in immunology and infectious disease. | 7 |
| 36738392 | 2023 | Sialoadhesin (CD169/Siglec-1) is an extended molecule that escapes inhibitory cis-interactions and synergizes with other macrophage receptors to promote phagocytosis. | 1 |
| 37061149 | 2023 | CD169 expression on monocytes as a marker for assessing type I interferon status in pediatric inflammatory diseases. | 3 |
| 34494938 | 2023 | The role of sialic acid-binding immunoglobulin-like-lectin-1 (siglec-1) in immunology and infectious disease. | 7 |
| 36738392 | 2023 | Sialoadhesin (CD169/Siglec-1) is an extended molecule that escapes inhibitory cis-interactions and synergizes with other macrophage receptors to promote phagocytosis. | 1 |
| 37061149 | 2023 | CD169 expression on monocytes as a marker for assessing type I interferon status in pediatric inflammatory diseases. | 3 |
| 34387304 | 2022 | Siglec-1 expression on monocytes is associated with the interferon signature in juvenile dermatomyositis and can predict treatment response. | 10 |
| 35177553 | 2022 | SIGLEC1 enables straightforward assessment of type I interferon activity in idiopathic inflammatory myopathies. | 6 |
| 35695299 | 2022 | The role of activated monocyte IFN/SIGLEC1 signalling in Graves' disease. | 0 |
| 36279285 | 2022 | CD169-mediated restrictive SARS-CoV-2 infection of macrophages induces pro-inflammatory responses. | 12 |
| 34387304 | 2022 | Siglec-1 expression on monocytes is associated with the interferon signature in juvenile dermatomyositis and can predict treatment response. | 10 |
| 35177553 | 2022 | SIGLEC1 enables straightforward assessment of type I interferon activity in idiopathic inflammatory myopathies. | 6 |
| 35695299 | 2022 | The role of activated monocyte IFN/SIGLEC1 signalling in Graves' disease. | 0 |
Citation
Dessen P
SIGLEC1 (sialic acid binding Ig like lectin 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-03-01
Online version: http://atlasgeneticsoncology.org/gene/53829/siglec1-(sialic-acid-binding-ig-like-lectin-1)
