TTYH1 (tweety family member 1)

2014-03-01  

Identity

HGNC
TTYH1
LOCATION
19q13.42
LOCUSID
57348
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 57348
MIM: 605784
HGNC: 13476
Ensembl: ENSG00000167614

Variants:

dbSNP: 57348
ClinVar: 57348
TCGA: ENSG00000167614
COSMIC: TTYH1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167614ENST00000301194Q9H313
ENSG00000167614ENST00000376530Q9H313
ENSG00000167614ENST00000376531Q9H313
ENSG00000167614ENST00000391739G8JLI0
ENSG00000167614ENST00000423529C9J3K6
ENSG00000167614ENST00000425969F8WBE6
ENSG00000167614ENST00000445095E7ET67

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
Ion channel transportREACTOMER-HSA-983712
Stimuli-sensing channelsREACTOMER-HSA-2672351

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
378701932024Drosophila tweety facilitates autophagy to regulate mitochondrial homeostasis and bioenergetics in Glia.0
378701932024Drosophila tweety facilitates autophagy to regulate mitochondrial homeostasis and bioenergetics in Glia.0
343854452021Cryo-EM structures of the TTYH family reveal a novel architecture for lipid interactions.10
343854452021Cryo-EM structures of the TTYH family reveal a novel architecture for lipid interactions.10
286071722017Tweety-Homolog 1 Drives Brain Colonization of Gliomas.79
286071722017Tweety-Homolog 1 Drives Brain Colonization of Gliomas.79
243169812014Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR.95
251827042014Validation of analytical breast cancer microarray analysis in medical laboratory.2
243169812014Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR.95
251827042014Validation of analytical breast cancer microarray analysis in medical laboratory.2
185775132008The ubiquitin-protein ligase Nedd4-2 differentially interacts with and regulates members of the Tweety family of chloride ion channels.14
185775132008The ubiquitin-protein ligase Nedd4-2 differentially interacts with and regulates members of the Tweety family of chloride ion channels.14

Citation

Dessen P

TTYH1 (tweety family member 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-03-01

Online version: http://atlasgeneticsoncology.org/gene/53832