Identity
HGNC
LOCATION
5q22.2
LOCUSID
ALIAS
CAHL,hYTHDC2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64848
MIM: 616530
HGNC: 24721
Ensembl: ENSG00000047188
Variants:
dbSNP: 64848
ClinVar: 64848
TCGA: ENSG00000047188
COSMIC: YTHDC2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000047188 | ENST00000161863 | Q9H6S0 |
| ENSG00000047188 | ENST00000503857 | D6RF50 |
| ENSG00000047188 | ENST00000514720 | D6R9T8 |
| ENSG00000047188 | ENST00000515883 | D6RA70 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37162682 | 2024 | YTHDC2 Retards Cell Proliferation and Triggers Apoptosis in Papillary Thyroid Cancer by Regulating CYLD-Mediated Inactivation of Akt Signaling. | 2 |
| 38129673 | 2024 | The m6A Reader YTHDC2 Suppresses Lung Adenocarcinoma Tumorigenesis by Destabilizing MRPL12. | 1 |
| 37162682 | 2024 | YTHDC2 Retards Cell Proliferation and Triggers Apoptosis in Papillary Thyroid Cancer by Regulating CYLD-Mediated Inactivation of Akt Signaling. | 2 |
| 38129673 | 2024 | The m6A Reader YTHDC2 Suppresses Lung Adenocarcinoma Tumorigenesis by Destabilizing MRPL12. | 1 |
| 36644951 | 2023 | Overexpression of YTHDC2 contributes to the progression of prostate cancer and predicts poor outcomes in patients with prostate cancer. | 4 |
| 37474847 | 2023 | Crosstalk between RNA m(6)A and DNA methylation regulates transposable element chromatin activation and cell fate in human pluripotent stem cells. | 3 |
| 36644951 | 2023 | Overexpression of YTHDC2 contributes to the progression of prostate cancer and predicts poor outcomes in patients with prostate cancer. | 4 |
| 37474847 | 2023 | Crosstalk between RNA m(6)A and DNA methylation regulates transposable element chromatin activation and cell fate in human pluripotent stem cells. | 3 |
| 35138268 | 2022 | Pathogenic variants in the human m6A reader YTHDC2 are associated with primary ovarian insufficiency. | 8 |
| 35177478 | 2022 | The m(6)A reader YTHDC2 is essential for escape from KSHV SOX-induced RNA decay. | 16 |
| 36416324 | 2022 | Construction and clinical evaluation of N6-methyladenosine risk signature of YTHDC2, IGF2BP2, and HNRNPC in head and neck squamous cell carcinoma. | 0 |
| 36581942 | 2022 | lncRNA ZNRD1-AS1 promotes malignant lung cell proliferation, migration, and angiogenesis via the miR-942/TNS1 axis and is positively regulated by the m(6)A reader YTHDC2. | 17 |
| 35138268 | 2022 | Pathogenic variants in the human m6A reader YTHDC2 are associated with primary ovarian insufficiency. | 8 |
| 35177478 | 2022 | The m(6)A reader YTHDC2 is essential for escape from KSHV SOX-induced RNA decay. | 16 |
| 36416324 | 2022 | Construction and clinical evaluation of N6-methyladenosine risk signature of YTHDC2, IGF2BP2, and HNRNPC in head and neck squamous cell carcinoma. | 0 |
Citation
Dessen P
YTHDC2 (YTH domain containing 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-03-01
Online version: http://atlasgeneticsoncology.org/gene/53834
