FSIP1 (fibrous sheath interacting protein 1)

2014-03-01  

Identity

HGNC
LOCATION
15q14
LOCUSID
ALIAS
HSD10
FUSION GENES

Other Information

Locus ID:

NCBI: 161835
MIM: 615795
HGNC: 21674
Ensembl: ENSG00000150667

Variants:

dbSNP: 161835
ClinVar: 161835
TCGA: ENSG00000150667
COSMIC: FSIP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000150667ENST00000350221Q8NA03
ENSG00000150667ENST00000350221A0A024R9J2
ENSG00000150667ENST00000559547H0YNV9
ENSG00000150667ENST00000560769A0A2R8Y503
ENSG00000150667ENST00000642527A0A2R8YHB5

Expression (GTEx)

0
5
10
15

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA443450AsthmaDiseaseClinicalAnnotationassociatedPD
PA448497aspirinChemicalClinicalAnnotationassociatedPD

References

Pubmed IDYearTitleCitations
374607152023FSIP1 enhances the therapeutic sensitivity to CDK4/6 inhibitors in triple-negative breast cancer patients by activating the Nanog pathway.1
374607152023FSIP1 enhances the therapeutic sensitivity to CDK4/6 inhibitors in triple-negative breast cancer patients by activating the Nanog pathway.1
356928882022FSIP1 Is Associated with Poor Prognosis and Can Be Used to Construct a Prognostic Model in Gastric Cancer.1
356928882022FSIP1 Is Associated with Poor Prognosis and Can Be Used to Construct a Prognostic Model in Gastric Cancer.1
317139312020FSIP1 is correlated with estrogen receptor status and poor prognosis.5
327173082020Loss-of-function variants in FSIP1 identified by targeted sequencing are associated with one particular subtype of mucosal melanoma.2
317139312020FSIP1 is correlated with estrogen receptor status and poor prognosis.5
327173082020Loss-of-function variants in FSIP1 identified by targeted sequencing are associated with one particular subtype of mucosal melanoma.2
308144892019Over-expression of FSIP1 promotes breast cancer progression and confers resistance to docetaxel via MRP1 stabilization.14
308144892019Over-expression of FSIP1 promotes breast cancer progression and confers resistance to docetaxel via MRP1 stabilization.14
305099732018FSIP1 regulates autophagy in breast cancer.16
305099732018FSIP1 regulates autophagy in breast cancer.16
280862392017Elevated fibrous sheath interacting protein 1 levels are associated with poor prognosis in non-small cell lung cancer patients.8
286740222017FSIP1 binds HER2 directly to regulate breast cancer growth and invasiveness.14
280862392017Elevated fibrous sheath interacting protein 1 levels are associated with poor prognosis in non-small cell lung cancer patients.8

Citation

Dessen P

FSIP1 (fibrous sheath interacting protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-03-01

Online version: http://atlasgeneticsoncology.org/gene/53844/fsip1-(fibrous-sheath-interacting-protein-1)