Identity
HGNC
LOCATION
2q31.1
LOCUSID
ALIAS
CPSQ1,DEE89,GAD,SCP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2571
MIM: 605363
HGNC: 4092
Ensembl: ENSG00000128683
Variants:
dbSNP: 2571
ClinVar: 2571
TCGA: ENSG00000128683
COSMIC: GAD1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA444460 | Heroin Dependence | Disease | ClinicalAnnotation | associated | PD | 31866536 | |
| PA450401 | methadone | Chemical | ClinicalAnnotation | associated | PD | 31866536 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34845648 | 2022 | A preliminary genetic association study of GAD1 and GABAB receptor genes in patients with treatment-resistant schizophrenia. | 6 |
| 35023669 | 2022 | Evaluation of the Diagnostic and Predictive Value of Glutamic Acid Decarboxylase, Zinc Transporter 8 Serum Levels in Alzheimer's Disease. | 0 |
| 34845648 | 2022 | A preliminary genetic association study of GAD1 and GABAB receptor genes in patients with treatment-resistant schizophrenia. | 6 |
| 35023669 | 2022 | Evaluation of the Diagnostic and Predictive Value of Glutamic Acid Decarboxylase, Zinc Transporter 8 Serum Levels in Alzheimer's Disease. | 0 |
| 34125398 | 2021 | Interacting Roles of COMT and GAD1 Genes in Patients with Treatment-Resistant Schizophrenia: a Genetic Association Study of Schizophrenia Patients and Healthy Controls. | 5 |
| 34310624 | 2021 | Exploring the relationship between white matter integrity, cocaine use and GAD polymorphisms using Bayesian Model Averaging. | 0 |
| 34638827 | 2021 | Cannabinoid Receptor Type 1 Regulates Drug Reward Behavior via Glutamate Decarboxylase 67 Transcription. | 1 |
| 34125398 | 2021 | Interacting Roles of COMT and GAD1 Genes in Patients with Treatment-Resistant Schizophrenia: a Genetic Association Study of Schizophrenia Patients and Healthy Controls. | 5 |
| 34310624 | 2021 | Exploring the relationship between white matter integrity, cocaine use and GAD polymorphisms using Bayesian Model Averaging. | 0 |
| 34638827 | 2021 | Cannabinoid Receptor Type 1 Regulates Drug Reward Behavior via Glutamate Decarboxylase 67 Transcription. | 1 |
| 31866536 | 2020 | GAD1 but not GAD2 polymorphisms are associated with heroin addiction phenotypes. | 4 |
| 32282878 | 2020 | Bi-allelic GAD1 variants cause a neonatal onset syndromic developmental and epileptic encephalopathy. | 13 |
| 32514855 | 2020 | Glutamic acid decarboxylase antibodies in neurocritical patients: a culprit or a bystander? | 1 |
| 32705143 | 2020 | Early-infantile onset epilepsy and developmental delay caused by bi-allelic GAD1 variants. | 19 |
| 31866536 | 2020 | GAD1 but not GAD2 polymorphisms are associated with heroin addiction phenotypes. | 4 |
Citation
Dessen P
GAD1 (glutamate decarboxylase 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-03-01
Online version: http://atlasgeneticsoncology.org/gene/53845/gad1-(glutamate-decarboxylase-1)
