Identity
HGNC
LOCATION
4q21.22
LOCUSID
ALIAS
C15,DGIC,PNAS-144,onzin
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51316
MIM: 607515
HGNC: 19254
Ensembl: ENSG00000145287
Variants:
dbSNP: 51316
ClinVar: 51316
TCGA: ENSG00000145287
COSMIC: PLAC8
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Neutrophil degranulation | REACTOME | R-HSA-6798695 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36602585 | 2023 | PLAC8 contributes to the malignant behaviors of cervical cancer cells by activating the SOX4-mediated AKT pathway. | 0 |
| 37885015 | 2023 | Low m6A modification-mediated upregulation of PLAC8 promotes trophoblast cell invasion and migration in preeclampsia. | 0 |
| 36602585 | 2023 | PLAC8 contributes to the malignant behaviors of cervical cancer cells by activating the SOX4-mediated AKT pathway. | 0 |
| 37885015 | 2023 | Low m6A modification-mediated upregulation of PLAC8 promotes trophoblast cell invasion and migration in preeclampsia. | 0 |
| 34954560 | 2022 | Placenta-specific 8 (PLAC8) mediates inflammation and mobility of the hPDLCs via MEK/ERK signaling pathway. | 2 |
| 35279480 | 2022 | Long noncoding RNA HOXD-AS1 promotes the progression of pancreatic cancer through miR-664b-3p/PLAC8 axis. | 1 |
| 35497881 | 2022 | PLAC8 Overexpression Promotes Lung Cancer Cell Growth via Wnt/β-Catenin Signaling. | 6 |
| 36124427 | 2022 | Autophagy-linked plasma and lysosomal membrane protein PLAC8 is a key host factor for SARS-CoV-2 entry into human cells. | 10 |
| 36543379 | 2022 | Modification of PLAC8 by UFM1 affects tumorous proliferation and immune response by impacting PD-L1 levels in triple-negative breast cancer. | 6 |
| 34954560 | 2022 | Placenta-specific 8 (PLAC8) mediates inflammation and mobility of the hPDLCs via MEK/ERK signaling pathway. | 2 |
| 35279480 | 2022 | Long noncoding RNA HOXD-AS1 promotes the progression of pancreatic cancer through miR-664b-3p/PLAC8 axis. | 1 |
| 35497881 | 2022 | PLAC8 Overexpression Promotes Lung Cancer Cell Growth via Wnt/β-Catenin Signaling. | 6 |
| 36124427 | 2022 | Autophagy-linked plasma and lysosomal membrane protein PLAC8 is a key host factor for SARS-CoV-2 entry into human cells. | 10 |
| 36543379 | 2022 | Modification of PLAC8 by UFM1 affects tumorous proliferation and immune response by impacting PD-L1 levels in triple-negative breast cancer. | 6 |
| 33570788 | 2021 | PLAC8 promotes the autophagic activity and improves the growth priority of human trophoblast cells. | 11 |
Citation
Dessen P
PLAC8 (placenta associated 8)
Atlas Genet Cytogenet Oncol Haematol. 2014-03-01
Online version: http://atlasgeneticsoncology.org/gene/53850/plac8-(placenta-associated-8)
