REPIN1 (replication initiator 1)

2014-03-01  

Identity

HGNC
LOCATION
7q36.1
LOCUSID
ALIAS
AP4,RIP60,ZNF464,Zfp464
FUSION GENES

Other Information

Locus ID:

NCBI: 29803
HGNC: 17922
Ensembl: ENSG00000214022

Variants:

dbSNP: 29803
ClinVar: 29803
TCGA: ENSG00000214022
COSMIC: REPIN1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000214022ENST00000397281Q9BWE0
ENSG00000214022ENST00000397281A0A090N8H1
ENSG00000214022ENST00000425389Q9BWE0
ENSG00000214022ENST00000425389A0A090N8H1
ENSG00000214022ENST00000444957Q9BWE0
ENSG00000214022ENST00000444957A0A090N8H1
ENSG00000214022ENST00000466559C9J0L4
ENSG00000214022ENST00000467980C9J7D4
ENSG00000214022ENST00000475514C9JZE3
ENSG00000214022ENST00000479668C9J590
ENSG00000214022ENST00000482680C9J590
ENSG00000214022ENST00000486714C9J7L2
ENSG00000214022ENST00000488943C9JYJ8
ENSG00000214022ENST00000489432Q9BWE0
ENSG00000214022ENST00000518514E5RK52
ENSG00000214022ENST00000519397E7EVL6
ENSG00000214022ENST00000522266C9J7D4

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
377490792023REPIN1 regulates iron metabolism and osteoblast apoptosis in osteoporosis.1
377490792023REPIN1 regulates iron metabolism and osteoblast apoptosis in osteoporosis.1
333390692021Overexpression of miR-127 Predicts Poor Prognosis and Contributes to the Progression of Papillary Thyroid Cancer by Targeting REPIN1.2
333390692021Overexpression of miR-127 Predicts Poor Prognosis and Contributes to the Progression of Papillary Thyroid Cancer by Targeting REPIN1.2
319229942020A Human REPIN1 Gene Variant: Genetic Risk Factor for the Development of Nonalcoholic Fatty Liver Disease.2
319229942020A Human REPIN1 Gene Variant: Genetic Risk Factor for the Development of Nonalcoholic Fatty Liver Disease.2
299153652019Metabolic effects of genetic variation in the human REPIN1 gene.4
299153652019Metabolic effects of genetic variation in the human REPIN1 gene.4
293374282018AP4 positively regulates LAPTM4B to promote hepatocellular carcinoma growth and metastasis, while reducing chemotherapy sensitivity.15
299792592018Hsa-mir-127 impairs survival of patients with glioma and promotes proliferation, migration and invasion of cancerous cells by modulating replication initiator 1.8
293374282018AP4 positively regulates LAPTM4B to promote hepatocellular carcinoma growth and metastasis, while reducing chemotherapy sensitivity.15
299792592018Hsa-mir-127 impairs survival of patients with glioma and promotes proliferation, migration and invasion of cancerous cells by modulating replication initiator 1.8
252668052015Crosstalk of AP4 and TGFβ receptor signaling in NSCLC.5
260370742015AP4 activates cell migration and EMT mediated by p53 in MDA-MB-231 breast carcinoma cells.8
252668052015Crosstalk of AP4 and TGFβ receptor signaling in NSCLC.5

Citation

Dessen P

REPIN1 (replication initiator 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-03-01

Online version: http://atlasgeneticsoncology.org/gene/53851/repin1-(replication-initiator-1)