MYL9 (myosin light chain 9)

2014-04-01  

Identity

HGNC
LOCATION
20q11.23
LOCUSID
ALIAS
LC20,MLC-2C,MLC2,MRLC1,MYRL2
FUSION GENES

Other Information

Locus ID:

NCBI: 10398
MIM: 609905
HGNC: 15754
Ensembl: ENSG00000101335

Variants:

dbSNP: 10398
ClinVar: 10398
TCGA: ENSG00000101335
COSMIC: MYL9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000101335ENST00000279022P24844
ENSG00000101335ENST00000279022A0A384NY64
ENSG00000101335ENST00000346786P24844

Expression (GTEx)

0
1000
2000
3000
4000
5000
6000
7000
8000

Pathways

PathwaySourceExternal ID
Focal adhesionKEGGko04510
Tight junctionKEGGko04530
Leukocyte transendothelial migrationKEGGko04670
Regulation of actin cytoskeletonKEGGko04810
Focal adhesionKEGGhsa04510
Tight junctionKEGGhsa04530
Leukocyte transendothelial migrationKEGGhsa04670
Regulation of actin cytoskeletonKEGGhsa04810
Vascular smooth muscle contractionKEGGhsa04270
Vascular smooth muscle contractionKEGGko04270
Oxytocin signaling pathwayKEGGhsa04921
Oxytocin signaling pathwayKEGGko04921
cGMP-PKG signaling pathwayKEGGhsa04022
cGMP-PKG signaling pathwayKEGGko04022
cAMP signaling pathwayKEGGhsa04024
cAMP signaling pathwayKEGGko04024
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
RHO GTPase EffectorsREACTOMER-HSA-195258
RHO GTPases Activate ROCKsREACTOMER-HSA-5627117
RHO GTPases activate PAKsREACTOMER-HSA-5627123
RHO GTPases activate PKNsREACTOMER-HSA-5625740
RHO GTPases activate CITREACTOMER-HSA-5625900
Muscle contractionREACTOMER-HSA-397014
Smooth Muscle ContractionREACTOMER-HSA-445355
Developmental BiologyREACTOMER-HSA-1266738
Axon guidanceREACTOMER-HSA-422475
Semaphorin interactionsREACTOMER-HSA-373755
Sema4D in semaphorin signalingREACTOMER-HSA-400685
Sema4D induced cell migration and growth-cone collapseREACTOMER-HSA-416572
EPH-Ephrin signalingREACTOMER-HSA-2682334
EPHA-mediated growth cone collapseREACTOMER-HSA-3928663

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
378011992024LAMB3 Promotes Myofibrogenesis and Cytoskeletal Reorganization in Endometrial Stromal Cells via the RhoA/ROCK1/MYL9 Pathway.0
384723752024The interplay between alterations in esophageal microbiota associated with Th17 immune response and impaired LC20 phosphorylation in achalasia.1
378011992024LAMB3 Promotes Myofibrogenesis and Cytoskeletal Reorganization in Endometrial Stromal Cells via the RhoA/ROCK1/MYL9 Pathway.0
384723752024The interplay between alterations in esophageal microbiota associated with Th17 immune response and impaired LC20 phosphorylation in achalasia.1
379268352023MYL9 expressed in cancer-associated fibroblasts regulate the immune microenvironment of colorectal cancer and promotes tumor progression in an autocrine manner.2
379506702023MYL9 promotes squamous cervical cancer migration and invasion by enhancing aerobic glycolysis.0
379268352023MYL9 expressed in cancer-associated fibroblasts regulate the immune microenvironment of colorectal cancer and promotes tumor progression in an autocrine manner.2
379506702023MYL9 promotes squamous cervical cancer migration and invasion by enhancing aerobic glycolysis.0
347299292022The landscape of prognostic and immunological role of myosin light chain 9 (MYL9) in human tumors.13
348210712022Clinicopathological significance of MYL9 expression in pancreatic ductal adenocarcinoma.2
349747982022Myosin light chain 9 promotes the proliferation, invasion, migration and angiogenesis of colorectal cancer cells by binding to Yes-associated protein 1 and regulating Hippo signaling.10
358957162022Elevated Myl9 reflects the Myl9-containing microthrombi in SARS-CoV-2-induced lung exudative vasculitis and predicts COVID-19 severity.12
366855582022Increased Myosin light chain 9 expression during Kawasaki disease vasculitis.1
347299292022The landscape of prognostic and immunological role of myosin light chain 9 (MYL9) in human tumors.13
348210712022Clinicopathological significance of MYL9 expression in pancreatic ductal adenocarcinoma.2

Citation

Dessen P

MYL9 (myosin light chain 9)

Atlas Genet Cytogenet Oncol Haematol. 2014-04-01

Online version: http://atlasgeneticsoncology.org/gene/53856/myl9-(myosin-light-chain-9)